KEGG   ORTHOLOGY: K20575
Entry
K20575            Tight     KO                                     
Symbol
aprD4
Name
radical SAM diol-dehydratase
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R11274  
R11275  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20575  aprD4; radical SAM diol-dehydratase
Other DBs
COG: COG1032
Genes
AG: CAF33054(aprD4)
Reference
PMID:27120352
  Authors
Lv M, Ji X, Zhao J, Li Y, Zhang C, Su L, Ding W, Deng Z, Yu Y, Zhang Q
  Title
Characterization of a C3 Deoxygenation Pathway Reveals a Key Branch Point in Aminoglycoside Biosynthesis.
  Journal
J Am Chem Soc 138:6427-35 (2016)
DOI:10.1021/jacs.6b02221
  Sequence
[ag:CAF33054]
Reference
PMID:26879038
  Authors
Kim HJ, LeVieux J, Yeh YC, Liu HW
  Title
C3'-Deoxygenation of Paromamine Catalyzed by a Radical S-Adenosylmethionine Enzyme: Characterization of the Enzyme AprD4 and Its Reductase Partner AprD3.
  Journal
Angew Chem Int Ed Engl 55:3724-8 (2016)
DOI:10.1002/anie.201510635

  All links  
Ontology (2)   
   KEGG BRITE (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (1)   
   KEGG GENES (1)   
Literature (2)   
   PubMed (2)   
All databases (12)   

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