KEGG   ORTHOLOGY: K20588
Entry
K20588            Tight     KO                                     
Symbol
livN, parN
Name
5'''-epimerase [EC:5.1.3.-]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R11286  paromomycin-II 5'''-epimerase
R11288  5'''-epi-lividomycin-B 5'''-epimerase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20588  livN, parN; 5'''-epimerase
Other DBs
COG: COG0535
Genes
AG: CAF32379(parN) CAG38702(livN)
Reference
PMID:21689223
  Authors
Clausnitzer D, Piepersberg W, Wehmeier UF
  Title
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin.
  Journal
J Appl Microbiol 111:642-51 (2011)
DOI:10.1111/j.1365-2672.2011.05082.x
Reference
  Authors
Arya DP (ed).
  Title
Aminoglycoside antibiotics: From chemical biology to drug discovery
  Journal
Wiley-Interscience (2007)

  All links  
Ontology (2)   
   KEGG BRITE (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (2)   
   KEGG GENES (2)   
Literature (1)   
   PubMed (1)   
All databases (12)   

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