KEGG   ORTHOLOGY: K20592
Entry
K20592            Tight     KO                                     
Symbol
genN
Name
SAM-dependent 3''-N-methyltransferase [EC:2.1.1.-]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R11292  S-adenosyl-L-methionine:3''-dehydro-3''-amino-gentamicin-A2 N-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20592  genN; SAM-dependent 3''-N-methyltransferase
Other DBs
COG: COG2890
Genes
AG: CAF31454(genN)
Reference
PMID:26946376
  Authors
Ni X, Zong T, Zhang H, Gu Y, Huang M, Tian W, Xia H
  Title
Biosynthesis of 3''-demethyl-gentamicin C components by genN disruption strain of Micromonospora echinospora and test their antimicrobial activities in vitro.
  Journal
Microbiol Res 185:36-44 (2016)
DOI:10.1016/j.micres.2016.01.005
  Sequence
[ag:CAF31454]
Reference
PMID:25641167
  Authors
Huang C, Huang F, Moison E, Guo J, Jian X, Duan X, Deng Z, Leadlay PF, Sun Y
  Title
Delineating the biosynthesis of gentamicin x2, the common precursor of the gentamicin C antibiotic complex.
  Journal
Chem Biol 22:251-61 (2015)
DOI:10.1016/j.chembiol.2014.12.012

  All links  
Ontology (2)   
   KEGG BRITE (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (1)   
   KEGG GENES (1)   
Literature (2)   
   PubMed (2)   
All databases (12)   

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