KEGG   ORTHOLOGY: K20594
Entry
K20594            Tight     KO                                     
Symbol
genK, gacD, gntK
Name
gentamicin X2 methyltransferase [EC:2.1.1.390]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R13180  S-adenosyl-L-methionine:gentamicin X2 C6'-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20594  genK, gacD, gntK; gentamicin X2 methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.390  gentamicin X2 methyltransferase
     K20594  genK, gacD, gntK; gentamicin X2 methyltransferase
Other DBs
COG: COG1032
Genes
AG: CAF31440(genK)
Reference
PMID:23679096
  Authors
Kim HJ, McCarty RM, Ogasawara Y, Liu YN, Mansoorabadi SO, LeVieux J, Liu HW
  Title
GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.
  Journal
J Am Chem Soc 135:8093-6 (2013)
DOI:10.1021/ja312641f
  Sequence
[ag:CAF31440]

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1)   
   KEGG GENES (1)   
Literature (1)   
   PubMed (1)   
All databases (12)   

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