KEGG   ORTHOLOGY: K20681Help
Entry
K20681                      KO                                     

Name
ftdC
Definition
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197]
Pathway
ko00523  Polyketide sugar unit biosynthesis
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K20681  ftdC; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.197  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
     K20681  ftdC; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
BRITE hierarchy
Other DBs
RN: R09873
COG: COG1207
Genes
AG: AAS55721(fdtC)
TaxonomyKoalaUniProt
Reference
  Authors
Pfoestl A, Hofinger A, Kosma P, Messner P
  Title
Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T.
  Journal
J Biol Chem 278:26410-7 (2003)
DOI:10.1074/jbc.M300858200
  Sequence

KEGG   ENZYME: 2.3.1.197Help
Entry
EC 2.3.1.197                Enzyme                                 

Name
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase;
FdtC;
dTDP-D-Fucp3N acetylase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose = CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose [RN:R09873]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose [CPD:C19947]
Product
CoA [CPD:C00010];
dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose [CPD:C20156]
Comment
The product, dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose, is a component of the glycan chain of the crystalline bacterial cell surface layer protein (S-layer glycoprotein) of Aneurinibacillus thermoaerophilus.
History
EC 2.3.1.197 created 2012
Pathway
ec00523  Polyketide sugar unit biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K20681  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Reference
1  [PMID:12740380]
  Authors
Pfoestl A, Hofinger A, Kosma P, Messner P
  Title
Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T.
  Journal
J Biol Chem 278:26410-7 (2003)
DOI:10.1074/jbc.M300858200
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.197
IUBMB Enzyme Nomenclature: 2.3.1.197
ExPASy - ENZYME nomenclature database: 2.3.1.197
BRENDA, the Enzyme Database: 2.3.1.197

KEGG   REACTION: R09873Help
Entry
R09873                      Reaction                               

Name
acetyl-CoA:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
Definition
Acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose
Equation
Reaction class
RC00004  C00010_C00024
RC00166  C19947_C20156
Enzyme
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K20681  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197]
Other DBs
RHEA: 32098

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