KEGG   ORTHOLOGY: K20801
Entry
K20801                      KO                                     

Name
ltaA
Definition
L-allo-threonine aldolase [EC:4.1.2.49]
Pathway
ko00260  Glycine, serine and threonine metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    K20801  ltaA; L-allo-threonine aldolase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.2  Aldehyde-lyases
    4.1.2.49  L-allo-threonine aldolase
     K20801  ltaA; L-allo-threonine aldolase
Other DBs
RN: R06171
COG: COG2008
Genes
AHA: AHA_1795
AHY: AHML_09870
AHD: AI20_10070
AHR: V428_10130
AHP: V429_10135
AHJ: V469_13360
AHH: RY45_09770
AHI: VU14_13575
AAJ: BOQ57_08800
ASA: ASA_1753(ltaA)
AVR: B565_2324
AMED: B224_1834
ASR: WL1483_125(ltaA)
ACAV: VI35_12120
AEL: NCTC12917_02364(ltaA)
AG: BAA20404(ltaA)
 » show all
Reference
PMID:9228760
  Authors
Kataoka M, Wada M, Nishi K, Yamada H, Shimizu S
  Title
Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39.
  Journal
FEMS Microbiol Lett 151:245-8 (1997)
DOI:10.1111/j.1574-6968.1997.tb12577.x
  Sequence

KEGG   ENZYME: 4.1.2.49
Entry
EC 4.1.2.49                 Enzyme                                 

Name
L-allo-threonine aldolase
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
Sysname
L-allo-threonine acetaldehyde-lyase (glycine-forming)
Reaction(IUBMB)
L-allo-threonine = glycine + acetaldehyde [RN:R06171]
Reaction(KEGG)
R06171
Substrate
L-allo-threonine [CPD:C05519]
Product
glycine [CPD:C00037];
acetaldehyde [CPD:C00084]
Comment
Requires pyridoxal phosphate. This enzyme, characterized from the bacterium Aeromonas jandaei, is specific for L-allo-threonine and can not act on either L-threonine or L-serine. Different from EC 4.1.2.5, L-threonine aldolase, and EC 4.1.2.48, low-specificity L-threonine aldolase. A previously listed enzyme with this name, EC 4.1.2.6, was deleted in 1971 after it was found to be identical to EC 2.1.2.1, glycine hydroxymethyltransferase.
History
EC 4.1.2.49 created 2011
Pathway
ec00260  Glycine, serine and threonine metabolism
ec01100  Metabolic pathways
Orthology
K20801  L-allo-threonine aldolase
Genes
AHA: AHA_1795
AHY: AHML_09870
AHD: AI20_10070
AHR: V428_10130
AHP: V429_10135
AHJ: V469_13360
AHH: RY45_09770
AHI: VU14_13575
AAJ: BOQ57_08800
ASA: ASA_1753(ltaA)
AVR: B565_2324
AMED: B224_1834
ASR: WL1483_125(ltaA)
ACAV: VI35_12120
AEL: NCTC12917_02364(ltaA)
 » show all
Reference
1  [PMID:9228760]
  Authors
Kataoka M, Wada M, Nishi K, Yamada H, Shimizu S
  Title
Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39.
  Journal
FEMS Microbiol Lett 151:245-8 (1997)
DOI:10.1111/j.1574-6968.1997.tb12577.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.1.2.49
IUBMB Enzyme Nomenclature: 4.1.2.49
ExPASy - ENZYME nomenclature database: 4.1.2.49
BRENDA, the Enzyme Database: 4.1.2.49

KEGG   REACTION: R06171
Entry
R06171                      Reaction                               

Name
L-allo-threonine acetaldehyde-lyase (glycine-forming)
Definition
L-Allothreonine <=> Glycine + Acetaldehyde
Equation
Reaction class
RC00312  C00037_C05519
RC00372  C00084_C05519
Enzyme
4.1.2.48        4.1.2.49
Pathway
rn00260  Glycine, serine and threonine metabolism
rn01100  Metabolic pathways
Orthology
K01620  threonine aldolase [EC:4.1.2.48]
K20801  L-allo-threonine aldolase [EC:4.1.2.49]
Other DBs
RHEA: 26212

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