KEGG   ORTHOLOGY: K21052
Entry
K21052                      KO                                     

Name
TMEM5
Definition
alpha-dystroglycan beta1,4-xylosyltransferase [EC:2.4.2.61]
Pathway
ko00515  Mannose type O-glycan biosynthesis
ko01100  Metabolic pathways
Module
M00872  O-glycan biosynthesis, mannose type (core M3)
Disease
H00120  Muscular dystrophy-dystroglycanopathy type A
H02307  Muscular dystrophy-dystroglycanopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00515 Mannose type O-glycan biosynthesis
    K21052  TMEM5; alpha-dystroglycan beta1,4-xylosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K21052  TMEM5; alpha-dystroglycan beta1,4-xylosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.61  alpha-dystroglycan beta1,4-xylosyltransferase
     K21052  TMEM5; alpha-dystroglycan beta1,4-xylosyltransferase
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K21052  TMEM5; alpha-dystroglycan beta1,4-xylosyltransferase
Other DBs
RN: R12244
Genes
HSA: 10329(RXYLT1)
PTR: 452041(RXYLT1)
PPS: 100992813(TMEM5)
GGO: 101133488(RXYLT1)
PON: 100460186(RXYLT1)
NLE: 100584744(RXYLT1)
MCC: 717102(RXYLT1)
MCF: 102139236(TMEM5)
CSAB: 103238633(TMEM5)
RRO: 104680841(RXYLT1)
RBB: 108530040(TMEM5)
CJC: 100396930(TMEM5)
SBQ: 101051694(TMEM5)
MMU: 216395(Rxylt1)
MCAL: 110303339(Tmem5)
MPAH: 110326592(Tmem5)
RNO: 299841(Tmem5)
MUN: 110544358
CGE: 100757873(Rxylt1)
NGI: 103732350
HGL: 101716790(Tmem5) 106007506
CCAN: 109688718(Tmem5)
OCU: 100345411(TMEM5)
TUP: 102496430(TMEM5)
CFA: 608152(TMEM5)
VVP: 112922312(RXYLT1)
AML: 100464740(RXYLT1)
UMR: 103656829(TMEM5)
UAH: 113256338(RXYLT1)
ORO: 101385557(TMEM5)
ELK: 111159758
FCA: 101101235(TMEM5)
PTG: 102958532(TMEM5)
PPAD: 109270421(TMEM5)
AJU: 106981335(RXYLT1)
BTA: 515147(RXYLT1)
BOM: 102280602(TMEM5)
BIU: 109559282(TMEM5)
BBUB: 102406645(RXYLT1)
CHX: 102188924(TMEM5)
OAS: 101112124(RXYLT1)
SSC: 100155789(TMEM5)
CFR: 102515986(RXYLT1)
CDK: 105089266(RXYLT1)
BACU: 103019229(TMEM5)
LVE: 103083549(TMEM5)
OOR: 101289176(TMEM5)
DLE: 111173799(RXYLT1)
PCAD: 102973659(RXYLT1)
ECB: 100056566(RXYLT1)
EPZ: 103553856(TMEM5)
EAI: 106843751(TMEM5)
MYB: 102249341(TMEM5)
MYD: 102767891(TMEM5)
MNA: 107527142(TMEM5)
HAI: 109381648(TMEM5)
DRO: 112319159(RXYLT1)
PALE: 102877783(RXYLT1)
RAY: 107508215(TMEM5)
MJV: 108403882 108405319(TMEM5)
LAV: 100665764(RXYLT1)
TMU: 101347097
SHR: 100933243(RXYLT1)
PCW: 110203945 110204694 110211014(TMEM5)
OAA: 100086919(RXYLT1)
GGA: 417820(RXYLT1)
MGP: 100544427(RXYLT1)
CJO: 107310084(RXYLT1)
NMEL: 110392741(TMEM5)
APLA: 101796104(RXYLT1)
ACYG: 106047283(TMEM5)
TGU: 100218010(RXYLT1)
LSR: 110479854(RXYLT1)
SCAN: 103820429(RXYLT1)
GFR: 102039233(TMEM5)
FAB: 101807811(TMEM5)
PHI: 102110954(TMEM5)
PMAJ: 107205102(TMEM5)
CCAE: 111932408(RXYLT1)
CCW: 104698351(TMEM5)
ETL: 114059396(RXYLT1)
FPG: 101921640(TMEM5)
FCH: 102053891(RXYLT1)
CLV: 102086203(TMEM5)
EGZ: 104135953(TMEM5)
NNI: 104011529(TMEM5)
ACUN: 113491375(RXYLT1)
PADL: 103919977(TMEM5)
AAM: 106488143(TMEM5)
ASN: 102382915(RXYLT1)
AMJ: 102576823(TMEM5)
PSS: 102459090(RXYLT1)
CMY: 102939667(TMEM5)
CPIC: 101945589(TMEM5)
ACS: 100560359 103278900(tmem5)
PVT: 110075094(TMEM5)
PBI: 103064453(RXYLT1)
PMUR: 107293325(RXYLT1)
TSR: 106543805(TMEM5)
PMUA: 114605526(RXYLT1)
GJA: 107123401(TMEM5)
XLA: 446820(tmem5.S)
XTR: 100145540(rxylt1)
NPR: 108792582(TMEM5)
DRE: 557187(rxylt1)
SRX: 107722461 107738400
SANH: 107670366(tmem5) 107684684
SGH: 107559810 107587049
CCAR: 109110172(tmem5)
IPU: 108264772(tmem5)
PHYP: 113534283(rxylt1)
AMEX: 103039815(tmem5)
EEE: 113577197(rxylt1)
TRU: 101064249(rxylt1)
TNG: GSTEN00015931G001
LCO: 104923719(rxylt1)
NCC: 104949270(tmem5)
MZE: 101485151(rxylt1)
ONL: 100696362(rxylt1)
OLA: 101158942(rxylt1)
XMA: 102232454(rxylt1)
XCO: 114155264(rxylt1)
PRET: 103466210(tmem5)
CVG: 107082444(tmem5)
NFU: 107389076(tmem5)
KMR: 108237463(rxylt1)
ALIM: 106523189 106534997(tmem5)
AOCE: 111575928(tmem5)
CSEM: 103380416(tmem5)
POV: 109641917(tmem5)
LCF: 108875264(tmem5)
SDU: 111228597(tmem5)
SLAL: 111661770(rxylt1)
HCQ: 109530509(tmem5)
BPEC: 110161333(tmem5)
MALB: 109961858(tmem5)
SASA: 100380601(tmem5)
OTW: 112252554(rxylt1)
SALP: 111952823(rxylt1)
ELS: 105018139(rxylt1)
SFM: 108935981(rxylt1)
PKI: 111860961(rxylt1)
LCM: 102347491(TMEM5)
CMK: 103179815(tmem5)
RTP: 109927331(tmem5)
BFO: 118415550
CIN: 100176272
SPU: 583032
APLC: 110974336
SKO: 100371491
BTAB: 109039481
CLEC: 106669996
PHU: Phum_PHUM354410
ZNE: 110831162
DPX: DAPPUDRAFT_48489
PVM: 113803028
ISC: IscW_ISCW021970
TUT: 107359888 107363073
DPTE: 113794600
CSCU: 111635261
PTEP: 107455480
HRO: HELRODRAFT_191935
LGI: LOTGIDRAFT_228735
PCAN: 112571562
CRG: 105323570 105327647
MYI: 110443872
OBI: 106874473
LAK: 106150449 106167194
NVE: 5500853 5505848
EPA: 110238447 110251687
ADF: 107327964
AMIL: 114956532
PDAM: 113679018
SPIS: 111323979
DGT: 114526485
HMG: 101235002
TAD: TRIADDRAFT_19905
CVR: CHLNCDRAFT_136933
GSL: Gasu_16570
MBR: MONBRDRAFT_16245
SRE: PTSG_08361 PTSG_11330
ACAN: ACA1_058550
PIF: PITG_14617
PSOJ: PHYSODRAFT_302886
GTT: GUITHDRAFT_102172 GUITHDRAFT_115376
 » show all
Reference
  Authors
Manya H, Yamaguchi Y, Kanagawa M, Kobayashi K, Tajiri M, Akasaka-Manya K, Kawakami H, Mizuno M, Wada Y, Toda T, Endo T
  Title
The Muscular Dystrophy Gene TMEM5 Encodes a Ribitol beta1,4-Xylosyltransferase Required for the Functional Glycosylation of Dystroglycan.
  Journal
J Biol Chem 291:24618-24627 (2016)
DOI:10.1074/jbc.M116.751917
  Sequence
[hsa:10329]

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (2)   
   KEGG DISEASE (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Gene (1236)   
   KEGG GENES (201)   
   KEGG MGENES (574)   
   RefGene (455)   
   OC (6)   
Protein sequence (80)   
   UniProt (77)   
   SWISS-PROT (3)   
Literature (1)   
   PubMed (1)   
All databases (1329)   

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