KEGG   ORTHOLOGY: K21178
Entry
K21178                      KO                                     

Name
sgcD4
Definition
O-methyltransferase [EC:2.1.1.-]
Pathway
ko01059  Biosynthesis of enediyne antibiotics
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00826  C-1027 benzoxazolinate moiety biosynthesis, chorismate => benzoxazolinyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21178  sgcD4; O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-  
     K21178  sgcD4; O-methyltransferase
Other DBs
RN: R11364
COG: COG2890
Genes
SGB: WQO_33900
STRM: M444_37940
SRO: Sros_6962 Sros_6986
Reference
  Authors
Liu W, Christenson SD, Standage S, Shen B
  Title
Biosynthesis of the enediyne antitumor antibiotic C-1027.
  Journal
Science 297:1170-3 (2002)
DOI:10.1126/science.1072110
  Sequence
[sgb:WQO_33900]
Reference
  Authors
Van Lanen SG, Lin S, Shen B
  Title
Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism.
  Journal
Proc Natl Acad Sci U S A 105:494-9 (2008)
DOI:10.1073/pnas.0708750105

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (5)   
   KEGG GENES (4)   
   OC (1)   
Protein sequence (4)   
   UniProt (4)   
Literature (2)   
   PubMed (2)   
All databases (23)   

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KEGG   REACTION: R11364
Entry
R11364                      Reaction                               

Definition
3,4-Dihydro-7-hydroxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylate <=> 3,4-Dihydro-7-methoxy-2-methylene-3-oxo-2H-1,4-benzoxazine-5-carboxylic acid
Equation
Comment
methyltransferase
incomplete reaction
Reaction class
RC00392  C11468_C21307
Enzyme
2.1.1.-
Pathway
rn01059  Biosynthesis of enediyne antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00826  C-1027 benzoxazolinate moiety biosynthesis, chorismate => benzoxazolinyl-CoA
Orthology
K21178  O-methyltransferase [EC:2.1.1.-]

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (1)   
   KEGG RCLASS (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (4)   
All databases (16)   

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