KEGG   ORTHOLOGY: K21259
Entry
K21259                      KO                                     

Name
calG3
Definition
calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase [EC:2.4.1.-]
Pathway
ko01059  Biosynthesis of enediyne antibiotics
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21259  calG3; calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.-  
     K21259  calG3; calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase
Other DBs
RN: R11417
COG: COG1819
CAZy: GT1
Genes
SAQ: Sare_2033
AG: AAM94798(calG3)
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
  Authors
Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN Jr, Thorson JS
  Title
Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
  Journal
Chem Biol 15:842-53 (2008)
DOI:10.1016/j.chembiol.2008.06.011

KEGG   REACTION: R11417
Entry
R11417                      Reaction                               

Name
dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose:calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase
Definition
dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Calicheamicinone <=> dTDP + Calicheamicin T0
Equation
Reaction class
RC00005  C00363_C21348
RC00049  C21337_C21338
Enzyme
2.4.1.-
Pathway
rn01059  Biosynthesis of enediyne antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Orthology
K21259  calicheamicinone 4-hydroxyamino-4,6-dideoxy-alpha-D-glucosyltransferase [EC:2.4.1.-]

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