KEGG   ORTHOLOGY: K21262Help
Entry
K21262                      KO                                     

Name
calG4
Definition
calicheamicin aminopentosyltransferase [EC:2.4.2.-]
Pathway
ko01059  Biosynthesis of enediyne antibiotics
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21262  calG4; calicheamicin aminopentosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.-  
     K21262  calG4; calicheamicin aminopentosyltransferase
BRITE hierarchy
Other DBs
RN: R11420 R11421
COG: COG1819
CAZy: GT1
Genes
SAQ: Sare_2021
AG: AAM70365(calG4)
TaxonomyKoalaUniProt
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
  Authors
Zhang C, Griffith BR, Fu Q, Albermann C, Fu X, Lee IK, Li L, Thorson JS
  Title
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions.
  Journal
Science 313:1291-4 (2006)
DOI:10.1126/science.1130028

KEGG   REACTION: R11421Help
Entry
R11421                      Reaction                               

Name
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose:calicheamicin-alpha3(I) 4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentosyltransferase
Definition
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin alpha3(I) <=> dTDP + Calicheamicin gamma(1)I
Equation
Reaction class
RC00005  C00363_C21356
RC00049  C11469_C21342
Enzyme
2.4.2.-
Pathway
rn01059  Biosynthesis of enediyne antibiotics
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Orthology
K21262  calicheamicin aminopentosyltransferase [EC:2.4.2.-]

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