KEGG   ORTHOLOGY: K21268
Entry
K21268                      KO                                     
Symbol
gdS-2
Name
hexaprenyl diphosphate synthase [EC:2.5.1.82]
Pathway
map00900  Terpenoid backbone biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R09246  geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase (adding 2 isopentenyl units)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K21268  gdS-2; hexaprenyl diphosphate synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K21268  gdS-2; hexaprenyl diphosphate synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.82  hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
     K21268  gdS-2; hexaprenyl diphosphate synthase
Prenyltransferases [BR:ko01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   K21268  gdS-2; hexaprenyl diphosphate synthase
Other DBs
COG: COG0142
GO: 0052922
Genes
STO: STK_04870
SOH: D1869_02255
SSO: SSO2345(gdS-2)
SOL: Ssol_0157
SSOA: SULA_0149
SSOL: SULB_0150
SSOF: SULC_0149
SSHI: J5U23_01140
SCAS: SACC_19450
SAI: Saci_0995
SID: M164_0161
SII: LD85_0146
SIH: SiH_0146
SIR: SiRe_0142
SIC: SiL_0133
MSE: Msed_0691
MEMJ: MJ1HA_0801
MCN: Mcup_1409
AHO: Ahos_2145
ACIH: HS5_09560
CSTY: KN1_02790
STEP: IC006_2729
SMET: RQ359_001711(gdS-2)
SAHS: HS7_16810
 » show all
Reference
  Authors
Hemmi H, Ikejiri S, Yamashita S, Nishino T
  Title
Novel medium-chain prenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus solfataricus.
  Journal
J Bacteriol 184:615-20 (2002)
DOI:10.1128/JB.184.3.615-620.2002
  Sequence
[sso:SSO2345]

KEGG   ORTHOLOGY: K05355
Entry
K05355                      KO                                     
Symbol
hexPS, COQ1
Name
hexaprenyl diphosphate synthase [EC:2.5.1.82 2.5.1.83]
Pathway
map00900  Terpenoid backbone biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R09245  (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units)
R09246  geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase (adding 2 isopentenyl units)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.82  hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific]
     K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
    2.5.1.83  hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]
     K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
Prenyltransferases [BR:ko01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   K05355  hexPS, COQ1; hexaprenyl diphosphate synthase
Other DBs
COG: COG0142
Genes
CME: CYME_CMJ246C
SCE: YBR003W(COQ1)
SEUB: DI49_0184
SPAO: SPAR_B01070
AGO: AGOS_AER004W
ERC: Ecym_5300
KLA: KLLA0_E17183g
KMX: KLMA_60114(COQ1)
LTH: KLTH0G16368g
VPO: Kpol_1036p41
CGR: 2886824(GVI51_C04037)
NCS: NCAS_0I01970(NCAS0I01970)
NDI: NDAI_0A06570(NDAI0A06570)
TPF: TPHA_0A04460(TPHA0A04460)
TBL: TBLA_0F00560(TBLA0F00560)
TDL: TDEL_0D04200(TDEL0D04200)
KAF: KAFR_0F02550(KAFR0F02550)
KNG: KNAG_0J01180(KNAG0J01180)
PIC: PICST_86778(COQ1)
LEL: PVL30_000484(COQ1)
LBG: 92205789(LODBEIA_P05930)
CAL: CAALFM_CR00570WA(CaO19.7478)
CTEN: 18246326(COQ1)
YLI: 2909963(YALI2_B00439g)
SLB: AWJ20_394(COQ1)
NCR: NCU02305
NTE: NEUTE1DRAFT124027(NEUTE1DRAFT_124027)
SMP: 10801768(SMAC4_08723)
PBEL: QC761_509670(COQ1)
PPSD: QC762_509670(COQ1)
PPSP: QC763_509670(COQ1)
PPSA: QC764_509670(COQ1)
MGR: MGG_03343
PGRI: PgNI_00709
SSCK: SPSK_04068
TATV: 25779678(TrAtP1_008741)
TASP: 36617842(TrAFT101_002694)
MAJ: MAA_03330
MBRN: 26246070(G6M90_00g085240)
CMT: CCM_00496
PLJ: 28884193(PLICBS_005461)
PTKZ: JDV02_003904(COQ1)
BFU: BCIN_02g05540(Bccoq1)
MBE: MBM_07123
ALUC: AKAW2_80893A(COQ1)
ACHE: ACHE_70473A(COQ1)
APUU: APUU_31174S(COQ1)
ABE: ARB_07252
TVE: TRV_03960
PTE: PTT_13690
PTRR: 6338962(PtrM4_028830)
ZTR: MYCGRDRAFT_73426(COQ1)
SPO: 2541402(dps1)
SOM: SOMG_02290(dps1)
CNE: CNI01740
CNB: CNBH1650
CDEU: CNBG_2676
CDEP: 91090354(L203_106146)
KMG: 30163645(I203_102858)
KNE: 92182342(IAR55_005084)
CCAC: CcaHIS019_0305350(COQ1)
ABP: AGABI1DRAFT117445(AGABI1DRAFT_117445) AGABI1DRAFT121951(AGABI1DRAFT_121951)
ABV: AGABI2DRAFT123328(AGABI2DRAFT_123328) AGABI2DRAFT214023(AGABI2DRAFT_214023)
SCM: SCHCO_02488796(SCHCODRAFT_02488796) SCHCO_02492233(SCHCODRAFT_02492233) SCHCO_02641733(SCHCODRAFT_02641733) SCHCO_02697952(SCHCODRAFT_02697952)
MGL: MGL_1241
MRT: MRET_2902
DFA: DFA_03641(coq1)
 » show all
Reference
PMID:2198286
  Authors
Ashby MN, Edwards PA
  Title
Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase.
  Journal
J Biol Chem 265:13157-64 (1990)
  Sequence
[sce:YBR003W]

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