KEGG ORTHOLOGY: K21278

ORTHOLOGY: K21278

Entry

K21278                      KO

Symbol

DUSP1

Name

dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]

Pathway

map04010

MAPK signaling pathway

map04726

Serotonergic synapse

map05012

Parkinson disease

map05418

Fluid shear stress and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K21278  DUSP1; dual specificity protein phosphatase 1
09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    K21278  DUSP1; dual specificity protein phosphatase 1
09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    K21278  DUSP1; dual specificity protein phosphatase 1
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K21278  DUSP1; dual specificity protein phosphatase 1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K21278  DUSP1; dual specificity protein phosphatase 1
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K21278  DUSP1; dual specificity protein phosphatase 1
    3.1.3.48  protein-tyrosine-phosphatase
     K21278  DUSP1; dual specificity protein phosphatase 1
Protein phosphatases and associated proteins [BR:ko01009]
Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    K21278  DUSP1; dual specificity protein phosphatase 1

Other DBs

GO:	0017017 0004725

Genes

HSA:	1843(DUSP1)

PTR:	471742(DUSP1)

PPS:	100978783(DUSP1)

GGO:	101145560(DUSP1)

PON:	100435862(DUSP1)

PPYG:

129036959(DUSP1)

NLE:	100591464(DUSP1)

HMH:	116471853(DUSP1)

SSYN:

129486007(DUSP1)

MCC:	702981(DUSP1)

MCF:	102116284(DUSP1)

MTHB:

126956345

MNI:	105480878(DUSP1)

CSAB:

103244980(DUSP1)

CATY:

105581659(DUSP1)

PANU:

100997568(DUSP1)

TGE:	112625873(DUSP1)

MLEU:

105544972(DUSP1)

RRO:	104670131(DUSP1)

RBB:	108520017(DUSP1)

TFN:	117065462(DUSP1)

PTEH:

111547221(DUSP1)

CANG:

105515851(DUSP1)

CJC:	100393730(DUSP1)

SBQ:	101043469(DUSP1)

CIMI:

108317308(DUSP1)

ANAN:

105723244(DUSP1)

CSYR:

103252868(DUSP1)

MMUR:

105871862(DUSP1)

LCAT:

123637948(DUSP1)

PCOQ:

105814660(DUSP1)

OGA:	100945193(DUSP1)

MMU:	19252(Dusp1)

MCAL:

110312644(Dusp1)

MPAH:

110337954(Dusp1)

RNO:	114856(Dusp1)

MCOC:

116078286(Dusp1)

ANU:	117711593(Dusp1)

MUN:	110547818(Dusp1)

CGE:	100769474(Dusp1)

MAUA:

101831197(Dusp1)

PROB:

127219450(Dusp1)

PLEU:

114709487(Dusp1)

MORG:

121464047(Dusp1)

MFOT:

126498056

AAMP:

119812340(Dusp1)

NGI:	103748194(Dusp1)

HGL:	101701425(Dusp1)

CPOC:

100725668(Dusp1)

CCAN:

109694781(Dusp1)

DORD:

105985414(Dusp1)

DSP:	122099537(Dusp1)

PLOP:

125342070(Dusp1)

NCAR:

124987585

MMMA:

107147958(Dusp1)

OCU:

100340993

OPI:	101531665(DUSP1)

TUP:	102481474(DUSP1)

GVR:	103595912(DUSP1)

CFA:	489117(DUSP1)

CLUD:

112651454(DUSP1)

VVP:	112926138(DUSP1)

VLG:	121488137(DUSP1)

NPO:	129509959(DUSP1)

AML:	100483084(DUSP1)

UMR:	103664491(DUSP1)

UAH:	113264095(DUSP1)

UAR:	123788597(DUSP1)

ELK:

111140958

LLV:

125100671

MPUF:

101693585(DUSP1)

MNP:	132028425(DUSP1)

MLK:	131831918(DUSP1)

NVS:	122892752(DUSP1)

ORO:	101376261(DUSP1)

EJU:	114208648(DUSP1)

ZCA:	113929802(DUSP1)

MLX:	118016761(DUSP1)

NSU:	110588080(DUSP1)

LWW:	102740993(DUSP1)

FCA:	101093416(DUSP1)

PYU:	121011080(DUSP1)

PCOO:

112861350(DUSP1)

PBG:	122492214(DUSP1)

PVIV:

125175007(DUSP1)

LRUF:

124520324

PTG:	102960774(DUSP1)

PPAD:

109267510(DUSP1)

PUC:

125934994

AJU:

106975373

HHV:	120234102(DUSP1)

BTA:	539175(DUSP1)

BOM:	102266766(DUSP1)

BIU:	109574921(DUSP1)

BBUB:

102410828(DUSP1)

BBIS:

104996902(DUSP1)

CHX:	102180080(DUSP1)

OAS:	101107632(DUSP1)

BTAX:

128065956(DUSP1)

ODA:	120879670(DUSP1)

CCAD:

122454393(DUSP1)

MBEZ:

129553152(DUSP1)

SSC:	100522469(DUSP1)

CFR:	102505108(DUSP1)

CBAI:

105082649(DUSP1)

CDK:	105089401(DUSP1)

VPC:	102538892(DUSP1)

BACU:

103004641(DUSP1)

BMUS:

118893064(DUSP1)

LVE:	103073987(DUSP1)

OOR:	101278083(DUSP1)

DLE:	111185473(DUSP1)

PCAD:

102994142(DUSP1)

PSIU:

116751751(DUSP1)

NASI:

112405122(DUSP1)

ECB:	100069834(DUSP1)

EPZ:	103542920(DUSP1)

EAI:	106837352(DUSP1)

MYB:	102264079(DUSP1)

MYD:	102760550(DUSP1)

MMYO:

118658302(DUSP1)

MLF:	102434907(DUSP1)

MDT:	132235968(DUSP1)

PKL:	118711557(DUSP1)

EFUS:

103291549(DUSP1)

MNA:	107535716(DUSP1)

DRO:	112319677(DUSP1)

SHON:

118994956(DUSP1)

AJM:	119036235(DUSP1)

PDIC:

114510076(DUSP1)

PHAS:

123813204(DUSP1)

MMF:	118615867(DUSP1)

PPAM:

129066477(DUSP1)

HAI:	109379363(DUSP1)

RFQ:	117016981(DUSP1)

PALE:

102894546(DUSP1)

PGIG:

120615021(DUSP1)

PVP:	105299303(DUSP1)

RAY:	107511030(DUSP1)

MJV:	108398732(DUSP1)

TOD:	119235228(DUSP1)

SARA:

101553959(DUSP1)

SETR:

126012235(DUSP1)

LAV:	100665180(DUSP1)

TMU:

101352955

ETF:	101661665(DUSP1)

DNM:	101426146(DUSP1)

MDO:	100031265(DUSP1)

GAS:	123237492(DUSP1)

SHR:	100923908(DUSP1)

AFZ:

127550205

PCW:	110196069(DUSP1)

TVP:	118844142(DUSP1)

OAA:	100076090(DUSP1)

GGA:	374192(DUSP1)

PCOC:

116232035(DUSP1)

MGP:	100546569(DUSP1)

CJO:	107320475(DUSP1)

TPAI:

128081637(DUSP1)

LMUT:

125700380(DUSP1)

NMEL:

110405394(DUSP1)

APLA:

101802393(DUSP1)

ACYG:

106042748(DUSP1)

CATA:

118254382(DUSP1)

AFUL:

116495021(DUSP1)

TGU:	100219518(DUSP1)

LSR:	110471461(DUSP1)

SCAN:

103824102(DUSP1)

PMOA:

120498639(DUSP1)

OTC:	121332379(DUSP1)

PRUF:

121365634(DUSP1)

GFR:	102033656(DUSP1)

FAB:	101821078(DUSP1)

OMA:	130258899(DUSP1)

PHI:	102114546(DUSP1)

PMAJ:

107210905(DUSP1)

CCAE:

111935377(DUSP1)

CCW:	104689650(DUSP1)

CBRC:

103611569(DUSP1)

ETL:	114066568(DUSP1)

ZAB:	102068767(DUSP1)

ZLE:	135453810(DUSP1)

ACHL:

103803993(DUSP1)

SVG:	106853004(DUSP1)

MMEA:

130586910(DUSP1)

HRT:	120759414(DUSP1)

SATI:

136367616(DUSP1)

FPG:	101917721(DUSP1)

FCH:	102053987(DUSP1)

NNT:	104411934(DUSP1)

SHAB:

115615889(DUSP1)

ACUN:

113485411(DUSP1)

TALA:

104363136(DUSP1)

ACHC:

115334328(DUSP1)

HALD:

104320040(DUSP1)

HLE:	104838995(DUSP1)

AGEN:

126050842

GCL:

127022068

CSTI:

104559941(DUSP1)

LDI:	104351976(DUSP1)

MNB:	103778990(DUSP1)

DPUB:

104303946(DUSP1)

AVIT:

104280282(DUSP1)

BRHI:

104496350(DUSP1)

EGZ:	104133636(DUSP1)

NNI:	104018968(DUSP1)

PCRI:

104027404(DUSP1)

PCAO:

104045232(DUSP1)

PADL:

103912304(DUSP1)

AFOR:

103904504(DUSP1)

GSTE:

104259287(DUSP1)

CLV:	102089263(DUSP1)

MUI:	104537598(DUSP1)

PGUU:

104469727(DUSP1)

PLET:

104627753(DUSP1)

CMAC:

104485259(DUSP1)

CUCA:

104065581(DUSP1)

TEO:	104381646(DUSP1)

BREG:

104630447(DUSP1)

OHA:	104332214(DUSP1)

ACAR:

104530417

CPEA:

104392648(DUSP1)

CVF:	104283862(DUSP1)

RTD:	128916349(DUSP1)

AAM:	106497521(DUSP1)

AROW:

112964735(DUSP1)

NPD:	112954502(DUSP1)

TGT:

104572807

DNE:	112996968(DUSP1)

SCAM:

104142462(DUSP1)

ASN:	102375445(DUSP1)

AMJ:	102559641(DUSP1)

CPOO:

109310009(DUSP1)

GGN:	109290041(DUSP1)

PSS:	102463448(DUSP1)

CMY:	102948279(DUSP1)

CCAY:

125641952(DUSP1)

DCC:	119860669(DUSP1)

CPIC:

101936270(DUSP1)

TST:	117881879(DUSP1)

CABI:

116837244(DUSP1)

MRV:	120370112(DUSP1)

ACS:	100557150(dusp1)

ASAO:

132768815(DUSP1)

PVT:	110086132(DUSP1)

SUND:

121923180(DUSP1)

PBI:	103061052(DUSP1)

PMUR:

107294676(DUSP1)

CTIG:

120311985(DUSP1)

TSR:	106540028(DUSP1)

PGUT:

117657383(DUSP1)

APRI:

131189813(DUSP1)

PTEX:

113433686(DUSP1)

NSS:	113425923(DUSP1)

VKO:	123035828(DUSP1)

PMUA:

114591047(DUSP1)

PRAF:

128407789(DUSP1)

ZVI:	118080296(DUSP1)

HCG:	128347342(DUSP1)

GJA:	107124748(DUSP1)

STOW:

125429842(DUSP1)

EMC:	129328422(DUSP1)

XLA:	380262(dusp1.L) 398254(dusp1.S)

XTR:	448043(dusp1)

NPR:	108788764(DUSP1)

RTEM:

120932271(DUSP1)

BBUF:

120978125(DUSP1)

BGAR:

122928163(DUSP1)

MUO:	115476326(DUSP1)

GSH:	117351557(DUSP1)

DRE:	406340(dusp1)

SRX:	107706733 107712309

SANH:

107660428 107679114

SGH:	107558048 107577187

CCAR:

109074644 109110063

CAUA:

113113377 113113503

CGIB:

127970913 128026918

PTET:

122357325(dusp1)

LROH:

127161711(dusp1)

OMC:	131553421(dusp1)

PPRM:

120464368(dusp1)

RKG:	130102854(dusp1)

MAMB:

125259015(dusp1)

CIDE:

127494586

CERY:

137019374(dusp1)

MASI:

127412852 127418396

TROS:

130564183(dusp1)

TDW:	130438409(dusp1)

MANU:

129421845(dusp1)

IPU:

108268678

IFU:	128611097(dusp1)

PHYP:

113542903(dusp1)

SMEO:

124386498(dusp1)

TFD:	113647798(dusp1)

TVC:	132855519(dusp1)

TRN:	134319587(dusp1)

AMEX:

103038437(dusp1)

CMAO:

118807327(dusp1)

EEE:

113576529

CHAR:

105906318(dusp1)

TRU:	101074284(dusp1)

TFS:	130531020(dusp1)

TNG:	GSTEN00017097G001

LCO:	104936101(dusp1)

NCC:	104959297(dusp1)

TBEN:

117475204(dusp1)

CGOB:

115014913(dusp1)

PGEO:

117454177(dusp1)

GACU:

117557009(dusp1)

EMAC:

134859632(dusp1)

ELY:	117261229(dusp1)

EFO:	125894304(dusp1)

PLEP:

121948033(dusp1)

SLUC:

116064228(dusp1)

ECRA:

117951932(dusp1)

ESP:	116697230(dusp1)

PFLV:

114562612(dusp1)

GAT:	120818003(dusp1)

PPUG:

119211338(dusp1)

AFB:	129089957(dusp1)

CLUM:

117737683(dusp1)

PSWI:

130209503(dusp1)

MSAM:

119889382(dusp1)

SCHU:

122879987(dusp1)

CUD:	121516018(dusp1)

ALAT:

119007720(dusp1)

MZE:	101487702(dusp1)

ONL:	100694058(dusp1)

OAU:	116324554(dusp1)

OLA:	101173794(dusp1)

OML:	112153347(dusp1)

CSAI:

133446865(dusp1)

XMA:	102232508(dusp1)

XCO:	114139363(dusp1)

XHE:	116714079(dusp1)

PRET:

103471107(dusp1)

PFOR:

103144546(dusp1)

PLAI:

106947098(dusp1)

PMEI:

106929685(dusp1)

GAF:	122837415(dusp1)

PPRL:

129362495(dusp1)

CVG:	107093461(dusp1)

CTUL:

119783207(dusp1)

GMU:	124859767(dusp1)

NFU:	107394133(dusp1)

KMR:	108242066(dusp1)

ALIM:

106510863(dusp1)

NWH:	119409059(dusp1)

AOCE:

111578781(dusp1)

MCEP:

125008164(dusp1)

CSEM:

103391114(dusp1)

POV:	109647322(dusp1)

SSEN:

122778966(dusp1)

HHIP:

117768814(dusp1)

HSP:	118112328(dusp1)

PPLT:

128446110(dusp1)

SMAU:

118319688(dusp1)

LCF:

108882864

SDU:	111226686(dusp1)

SLAL:

111652061(dusp1)

XGL:	120785624(dusp1)

HCQ:	109515925(dusp1)

SSCV:

125977095

SBIA:

133509042(dusp1)

PEE:	133408031(dusp1)

PTAO:

133484927(dusp1)

BPEC:

110163462(dusp1)

MALB:

109968408(dusp1)

BSPL:

114864794(dusp1)

SJO:	128363308(dusp1)

SASA:

106604105 106611914

STRU:

115166291 115205790

OTW:	112241347 112241498(dusp1)

OMY:	110487960 110504465(dusp1)

OGO:	123994218(dusp1) 124011447

ONE:	115123656(dusp1)

OKI:	109880139 109883429

OKE:	118380385 127929767(dusp1)

SALP:

112076474 112077166

SNH:	120047837 120062585(dusp1)

CCLU:

121555999(dusp1) 121556112 121556118

ELS:	105026777(dusp1)

SFM:	108931840(dusp1)

PKI:	111857699(dusp1)

AANG:

118224188(dusp1)

LOC:	102688449(dusp1)

PSPA:

121297145 121324461

ARUT:

117412756 117431064

PSEX:

120542340(dusp1)

LCM:	102364866(DUSP1)

CMK:	103190804(dusp1)

RTP:	109914245(dusp1) 109924522

CPLA:

122543238 122556719(dusp1)

HOC:	132823180(dusp1) 132836846(dusp2)

LERI:

129701673(dusp1)

PMRN:

116940690 116941284(DUSP1)

LRJ:	133343516 133345571

BFO:

118413453

BBEL:

109485283

CIN:	778913(dusp1.2.4.5)

SKO:

PTRU:

MNZ:

VDE:

VJA:

CSCU:

CVS:	136977752 136979875

UDV:

129222434

LPOL:

106461504

LGI:	LOTGIDRAFT_54372

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:	124267559 124271659

CRG:

CVN:

MYI:

PMAX:

MCAF:

OSN:

LJP:	135466694 135468715

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

RES:

TAD:	TRIADDRAFT_14780

PCO:	PHACADRAFT_54994

SRE:	PTSG_10981

DFA:

DFA_09473

EIV:	EIN_488240

PIF:	PITG_13732

PSOJ:

PHYSODRAFT_315023

» show all

Reference

PMID:1406996

Authors

Keyse SM, Emslie EA

Title

Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase.

Journal

Nature 359:644-7 (1992)
DOI:10.1038/359644a0

Sequence

[hsa:1843]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (2)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (2)   
   KEGG ENZYME (2)   
Gene (1328)   
   KEGG GENES (470)   
   KEGG MGENES (119)   
   RefGene (725)   
   OC (14)   
Literature (1)   
   PubMed (1)   
All databases (1344)   

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