KEGG   ORTHOLOGY: K21283
Entry
K21283                      KO                                     

Name
BMP2
Definition
bone morphogenetic protein 2
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04350  TGF-beta signaling pathway
ko04390  Hippo signaling pathway
ko05200  Pathways in cancer
ko05217  Basal cell carcinoma
Disease
H00482  Brachydactyly
H02481  Syndromic disorder with short stature
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K21283  BMP2; bone morphogenetic protein 2
   04390 Hippo signaling pathway
    K21283  BMP2; bone morphogenetic protein 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K21283  BMP2; bone morphogenetic protein 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K21283  BMP2; bone morphogenetic protein 2
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    K21283  BMP2; bone morphogenetic protein 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K21283  BMP2; bone morphogenetic protein 2
   00536 Glycosaminoglycan binding proteins
    K21283  BMP2; bone morphogenetic protein 2
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K21283  BMP2; bone morphogenetic protein 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K21283  BMP2; bone morphogenetic protein 2
Other DBs
GO: 0070700
Genes
HSA: 650(BMP2)
PTR: 458090(BMP2)
PPS: 100967346(BMP2)
GGO: 101149410(BMP2)
PON: 100460853(BMP2)
NLE: 100586297(BMP2)
MCC: 718330(BMP2)
MCF: 102145501(BMP2)
CSAB: 103246725(BMP2)
RRO: 104681477(BMP2)
RBB: 108525104 108533001(BMP2)
CJC: 100408260(BMP2)
SBQ: 101050026(BMP2)
MMU: 12156(Bmp2)
MCAL: 110289488(Bmp2)
MPAH: 110318284(Bmp2)
RNO: 29373(Bmp2)
MUN: 110557991(Bmp2)
CGE: 100752564(Bmp2)
NGI: 103725543(Bmp2)
HGL: 101723419(Bmp2)
CCAN: 109677386(Bmp2)
OCU: 100009349(BMP2) 108175367
TUP: 102469552(BMP2)
CFA: 477162(BMP2)
VVP: 112930056(BMP2)
AML: 100465860(BMP2)
UMR: 103674423(BMP2)
UAH: 113258350(BMP2)
ORO: 101367237(BMP2)
ELK: 111141639
FCA: 100301987(BMP2)
PTG: 102961685(BMP2)
PPAD: 109274726(BMP2)
AJU: 106976426(BMP2)
BTA: 615037(BMP2)
BOM: 102268860(BMP2)
BIU: 109567176(BMP2)
BBUB: 102408388(BMP2)
CHX: 100860831(BMP2)
OAS: 101117688(BMP2)
SSC: 100157103(BMP2)
CFR: 102514653(BMP2)
CDK: 105101322(BMP2)
BACU: 103004284(BMP2)
LVE: 103070700(BMP2)
OOR: 101269813(BMP2)
DLE: 111165639(BMP2)
PCAD: 102978631(BMP2)
ECB: 100051701(BMP2)
EPZ: 103563779(BMP2)
EAI: 106823202(BMP2)
MYB: 102241256(BMP2)
MYD: 102768711(BMP2)
MNA: 107536373(BMP2)
HAI: 109383815(BMP2)
DRO: 112304048(BMP2)
PALE: 102886941(BMP2)
RAY: 107511521(BMP2)
MJV: 108403876(BMP2)
LAV: 100654878(BMP2)
MDO: 100031674(BMP2)
SHR: 100935094(BMP2)
PCW: 110207865(BMP2) 110215386
OAA: 100084030(BMP2) 114810112
GGA: 112532694 378779(BMP2)
FPG: 101922026(BMP2) 106112594
EGZ: 104128703(BMP2) 104129039
NNI: 104022480(BMP2)
ACUN: 113477994(BMP2) 113481610
AAM: 106490352(BMP2) 106497809
AMJ: 102564323(BMP2) 102574161(ADMP) 102575698
ACS: 100560955(bmp2) 103279318
PBI: 103059412(BMP2) 103064164
PMUR: 107285368(BMP2) 107299617
TSR: 106540084 106550496(BMP2)
XLA: 100036830(admp2.L) 378780(bmp2.S) 397873(bmp2.L)
XTR: 100494614(admp2) 548717(bmp2)
DRE: 100329171(bmp16) 140619(admp) 30631(bmp2a) 30632(bmp2b)
CMK: 103186457(bmp2)
RTP: 109915138(bmp2) 109930532
BFO: 118411660
SKO: 100303514(bmp2/4) 100303522(admp) 100313546(Admp2) 100313762 102800705
CFO: 105258916
DNX: 107167002
TUT: 107365276
DPTE: 113793239
CSCU: 111621682
CBR: CBG19011(Cbr-dbl-1)
BMY: Bm1_52060
PCAN: 112569894
CRG: 105333366
EPA: 110243875
ADF: 107334071(AdiBmp2/4)
DGT: 114532337
 » show all
Reference
PMID:3201241
  Authors
Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whitters MJ, Kriz RW, Hewick RM, Wang EA
  Title
Novel regulators of bone formation: molecular clones and activities.
  Journal
Science 242:1528-34 (1988)
DOI:10.1126/science.3201241
  Sequence
[hsa:650]

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