KEGG   ORTHOLOGY: K21294
Entry
K21294                      KO                                     

Name
GLIC, ACLC, ROQR
Definition
gliotoxin/aspirochlorine/mycotoxins biosynthesis cytochrome P450 monooxygenase [EC:1.-.-.-]
Pathway
ko00404  Staurosporine biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K21294  GLIC, ACLC, ROQR; gliotoxin/aspirochlorine/mycotoxins biosynthesis cytochrome P450 monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.-  
   1.-.-  
    1.-.-.-  
     K21294  GLIC, ACLC, ROQR; gliotoxin/aspirochlorine/mycotoxins biosynthesis cytochrome P450 monooxygenase
Other DBs
RN: R12438 R12440
COG: COG2124
Genes
EPA: 110235416
ADF: 107341860
AMIL: 114974703 114975373
PDAM: 113669644
DGT: 114534845
KLA: KLLA0_C19206g
ZMK: HG535_0E00120
CAUR: CJI97_001079
MGR: MGG_16917
TMN: UCRPA7_6618
MAJ: MAA_00972
ANG: ANI_1_976084(An09g00560)
CIM: CIMG_11806(CIMG06709)
ZTR: MYCGRDRAFT_36631(CYP-39)
 » show all
Reference
  Authors
Gardiner DM, Howlett BJ
  Title
Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus.
  Journal
FEMS Microbiol Lett 248:241-8 (2005)
DOI:10.1016/j.femsle.2005.05.046
  Sequence
Reference
  Authors
Chang SL, Chiang YM, Yeh HH, Wu TK, Wang CC
  Title
Reconstitution of the early steps of gliotoxin biosynthesis in Aspergillus nidulans reveals the role of the monooxygenase GliC.
  Journal
Bioorg Med Chem Lett 23:2155-7 (2013)
DOI:10.1016/j.bmcl.2013.01.099
  Sequence
Reference
  Authors
Chankhamjon P, Boettger-Schmidt D, Scherlach K, Urbansky B, Lackner G, Kalb D, Dahse HM, Hoffmeister D, Hertweck C
  Title
Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion.
  Journal
Angew Chem Int Ed Engl 53:13409-13 (2014)
DOI:10.1002/anie.201407624
  Sequence

KEGG   REACTION: R12438
Entry
R12438                      Reaction                               

Definition
Histidyltryptophyldiketopiperazine <=> Dehydrohistidyltryptophyldiketopiperazine
Equation
Comment
cytochrome P450 oxidoreductase
Reaction class
RC03126  C22162_C22164
Enzyme
1.-.-.-
Pathway
rn00404  Staurosporine biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K21294  gliotoxin/aspirochlorine/mycotoxins biosynthesis cytochrome P450 monooxygenase [EC:1.-.-.-]

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