KEGG   ORTHOLOGY: K21310
Entry
K21310                      KO                                     

Name
mddA
Definition
methanethiol S-methyltransferase [EC:2.1.1.334]
Pathway
ko00920  Sulfur metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00920 Sulfur metabolism
    K21310  mddA; methanethiol S-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.334  methanethiol S-methyltransferase
     K21310  mddA; methanethiol S-methyltransferase
Other DBs
RN: R11546
COG: COG2020
Genes
YEL: LC20_02693
YHI: D5F51_08825
SLQ: M495_04985
PVC: G3341_08015
PSUW: WQ53_09920
LYJ: FKV23_01610
LSOL: GOY17_10880
XBC: ELE36_12935
DJA: HY57_09935
PRE: PCA10_21890
PFB: VO64_5660
PSET: THL1_2198
GPS: C427_2071
CYQ: Q91_2161
TIG: THII_1134
HCH: HCH_07018
KKO: Kkor_2188
SLIM: SCL_1908
SVA: SVA_3646
TBN: TBH_C2756
ENM: EBS_0312
RFR: Rfer_0359
HPSE: HPF_12860
CBAB: SMCB_1610
SLT: Slit_1216
AZA: AZKH_0967
SULR: B649_04520
SUN: SUN_0917
GME: Gmet_1980
GUR: Gura_2810
GLO: Glov_1324
PPD: Ppro_0660
DFL: DFE_1424
DBA: Dbac_2950
DAL: Dalk_2434
DALK: DSCA_45860
BJA: blr5741
AOL: S58_69050
RPA: RPA2835
RPT: Rpal_3176
NHA: Nham_4413
MET: M446_6423
MNO: Mnod_5015
MMED: Mame_05043
RDE: RD1_0738
DSH: Dshi_3401
HBA: Hbal_1129
SPHD: HY78_28265
SSAN: NX02_p1080
SINB: SIDU_12140
SPHT: K426_27180
ALB: AEB_P2660
ACR: Acry_3040
MAGX: XM1_0220
MAGN: WV31_03515
MAGQ: MGMAQ_0034
MGM: Mmc1_3239
DAE: Dtox_2171
CTHM: CFE_1060
CHY: CHY_1640
MTU: Rv3238c
MTC: MT3335
MRA: MRA_3279
MTUR: CFBS_3427
MTD: UDA_3238c
MTUC: J113_22575
MTUE: J114_17360
MTUH: I917_22710
MTUL: TBHG_03174
MTUT: HKBT1_3414
MTUU: HKBT2_3421
MBB: BCG_3267c
MBT: JTY_3263
MBX: BCGT_3104
MAF: MAF_32490
MMIC: RN08_3574
MPA: MAP_3351c
MAO: MAP4_0433
MAVI: RC58_02070
MAVU: RE97_02075
MAV: MAV_4200
MIT: OCO_40590
MIA: OCU_40500
MID: MIP_06116
MYO: OEM_40840
MIR: OCQ_41680
MLP: MLM_3359
MUL: MUL_2574
MMC: Mmcs_3486
MKM: Mkms_3549
MJL: Mjls_3499
MMI: MMAR_1307
MMM: W7S_20265
MVA: Mvan_2947
MSTE: MSTE_00408
MMIN: MMIN_32030
NFA: NFA_22060
ROP: ROP_13470
AMI: Amir_4657
ASE: ACPL_4161(nrm)
ACTS: ACWT_4032
AMR: AM1_2537
CYT: cce_1858
TER: Tery_4814
ATM: ANT_03710
OTE: Oter_4173
PSL: Psta_4588
MBAS: ALGA_3412
SLI: Slin_1791
WIN: WPG_2355
IAL: IALB_2999
MRO: MROS_1124
CPRV: CYPRO_2360
MBAK: MSBR3_0546
MAC: MA_2249
MMA: MM_2869
MMAC: MSMAC_1270
METM: MSMTP_1649
MHOR: MSHOH_1519
MMET: MCMEM_1540
MMH: Mmah_1061
BARC: AOA65_0751
AG: AJE75769(mddA)
 » show all
Reference
  Authors
Carrion O, Curson AR, Kumaresan D, Fu Y, Lang AS, Mercade E, Todd JD
  Title
A novel pathway producing dimethylsulphide in bacteria is widespread in soil environments.
  Journal
Nat Commun 6:6579 (2015)
DOI:10.1038/ncomms7579
  Sequence

KEGG   ENZYME: 2.1.1.334
Entry
EC 2.1.1.334                Enzyme                                 

Name
methanethiol S-methyltransferase;
mddA (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:methanethiol S-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + methanethiol = S-adenosyl-L-homocysteine + dimethyl sulfide [RN:R11546]
Reaction(KEGG)
R11546
Substrate
S-adenosyl-L-methionine [CPD:C00019];
methanethiol [CPD:C00409]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
dimethyl sulfide [CPD:C00580]
Comment
The enzyme, found in many bacterial taxa, is involved in a pathway that converts L-methionine to dimethyl sulfide.
History
EC 2.1.1.334 created 2016
Pathway
ec00920  Sulfur metabolism
ec01100  Metabolic pathways
Orthology
K21310  methanethiol S-methyltransferase
Genes
YEL: LC20_02693
YHI: D5F51_08825
SLQ: M495_04985
PVC: G3341_08015
PSUW: WQ53_09920
LYJ: FKV23_01610
LSOL: GOY17_10880
XBC: ELE36_12935
DJA: HY57_09935
PRE: PCA10_21890
PFB: VO64_5660
PSET: THL1_2198
GPS: C427_2071
CYQ: Q91_2161
TIG: THII_1134
HCH: HCH_07018
KKO: Kkor_2188
SLIM: SCL_1908
SVA: SVA_3646
TBN: TBH_C2756
ENM: EBS_0312
RFR: Rfer_0359
HPSE: HPF_12860
CBAB: SMCB_1610
SLT: Slit_1216
AZA: AZKH_0967
SULR: B649_04520
SUN: SUN_0917
GME: Gmet_1980
GUR: Gura_2810
GLO: Glov_1324
PPD: Ppro_0660
DFL: DFE_1424
DBA: Dbac_2950
DAL: Dalk_2434
DALK: DSCA_45860
BJA: blr5741
AOL: S58_69050
RPA: RPA2835
RPT: Rpal_3176
NHA: Nham_4413
MET: M446_6423
MNO: Mnod_5015
MMED: Mame_05043
RDE: RD1_0738
DSH: Dshi_3401
HBA: Hbal_1129
SPHD: HY78_28265
SSAN: NX02_p1080
SINB: SIDU_12140
SPHT: K426_27180
ALB: AEB_P2660
ACR: Acry_3040
MAGX: XM1_0220
MAGN: WV31_03515
MAGQ: MGMAQ_0034
MGM: Mmc1_3239
DAE: Dtox_2171
CTHM: CFE_1060
CHY: CHY_1640
MTU: Rv3238c
MTC: MT3335
MRA: MRA_3279
MTUR: CFBS_3427
MTD: UDA_3238c
MTUC: J113_22575
MTUE: J114_17360
MTUH: I917_22710
MTUL: TBHG_03174
MTUT: HKBT1_3414
MTUU: HKBT2_3421
MBB: BCG_3267c
MBT: JTY_3263
MBX: BCGT_3104
MAF: MAF_32490
MMIC: RN08_3574
MPA: MAP_3351c
MAO: MAP4_0433
MAVI: RC58_02070
MAVU: RE97_02075
MAV: MAV_4200
MIT: OCO_40590
MIA: OCU_40500
MID: MIP_06116
MYO: OEM_40840
MIR: OCQ_41680
MLP: MLM_3359
MUL: MUL_2574
MMC: Mmcs_3486
MKM: Mkms_3549
MJL: Mjls_3499
MMI: MMAR_1307
MMM: W7S_20265
MVA: Mvan_2947
MSTE: MSTE_00408
MMIN: MMIN_32030
NFA: NFA_22060
ROP: ROP_13470
AMI: Amir_4657
ASE: ACPL_4161(nrm)
ACTS: ACWT_4032
AMR: AM1_2537
CYT: cce_1858
TER: Tery_4814
ATM: ANT_03710
OTE: Oter_4173
PSL: Psta_4588
MBAS: ALGA_3412
SLI: Slin_1791
WIN: WPG_2355
IAL: IALB_2999
MRO: MROS_1124
CPRV: CYPRO_2360
MBAK: MSBR3_0546
MAC: MA_2249
MMA: MM_2869
MMAC: MSMAC_1270
METM: MSMTP_1649
MHOR: MSHOH_1519
MMET: MCMEM_1540
MMH: Mmah_1061
BARC: AOA65_0751
 » show all
Reference
1  [PMID:25807229]
  Authors
Carrion O, Curson AR, Kumaresan D, Fu Y, Lang AS, Mercade E, Todd JD
  Title
A novel pathway producing dimethylsulphide in bacteria is widespread in soil environments.
  Journal
Nat Commun 6:6579 (2015)
DOI:10.1038/ncomms7579
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.334
IUBMB Enzyme Nomenclature: 2.1.1.334
ExPASy - ENZYME nomenclature database: 2.1.1.334
BRENDA, the Enzyme Database: 2.1.1.334

KEGG   REACTION: R11546
Entry
R11546                      Reaction                               

Name
S-adenosyl-L-methionine:methanethiol S-methyltransferase
Definition
S-Adenosyl-L-methionine + Methanethiol <=> S-Adenosyl-L-homocysteine + Dimethyl sulfide
Equation
Reaction class
RC02653  C00409_C00580
Enzyme
Pathway
rn00920  Sulfur metabolism
rn01100  Metabolic pathways
Orthology
K21310  methanethiol S-methyltransferase [EC:2.1.1.334]
Other DBs
RHEA: 50431

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