KEGG   ORTHOLOGY: K21329Help
Entry
K21329                      KO                                     

Name
calE10
Definition
aminosugar N-oxygenase [EC:1.14.15.-]
Pathway
ko00523  Polyketide sugar unit biosynthesis
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K21329  calE10; aminosugar N-oxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.-  
     K21329  calE10; aminosugar N-oxygenase
BRITE hierarchy
Other DBs
RN: R11468
COG: COG2124
Genes
SAQ: Sare_2024
AG: AAM94800(calE10)
TaxonomyKoalaUniProt
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
  Authors
Johnson HD, Thorson JS
  Title
Characterization of CalE10, the N-oxidase involved in calicheamicin hydroxyaminosugar formation.
  Journal
J Am Chem Soc 130:17662-3 (2008)
DOI:10.1021/ja807557a

KEGG   REACTION: R11468Help
Entry
R11468                      Reaction                               

Name
dTDP-4-amino-4,6-dideoxy-D-glucose:reduced-ferredoxin:oxygen oxidoreductase
Definition
dTDP-4-amino-4,6-dideoxy-D-glucose + Reduced ferredoxin + Oxygen <=> dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Oxidized ferredoxin + H2O
Equation
Reaction class
RC03446  C04268_C21348
Enzyme
1.14.15.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K21329  aminosugar N-oxygenase [EC:1.14.15.-]

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