KEGG   ORTHOLOGY: K21333Help
Entry
K21333                      KO                                     

Name
calS14, atmS14
Definition
dTDP-4-oxo-alpha-D-xylose 2,3-dehydratase [EC:4.2.1.-]
Pathway
ko00523  Polyketide sugar unit biosynthesis
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K21333  calS14, atmS14; dTDP-4-oxo-alpha-D-xylose 2,3-dehydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.-  
     K21333  calS14, atmS14; dTDP-4-oxo-alpha-D-xylose 2,3-dehydratase
BRITE hierarchy
Other DBs
RN: R11473
Genes
SAQ: Sare_2025
AG: AAM70359(calS14) ABC02799(atmS14)
TaxonomyKoalaUniProt
Reference
PMID:26289554 (atmS14)
  Authors
Peltier-Pain P, Singh S, Thorson JS
  Title
Characterization of Early Enzymes Involved in TDP-Aminodideoxypentose Biosynthesis en Route to Indolocarbazole AT2433.
  Journal
Chembiochem 16:2141-6 (2015)
DOI:10.1002/cbic.201500365
  Sequence
Reference
PMID:12183629 (calS14)
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence

KEGG   REACTION: R11473Help
Entry
R11473                      Reaction                               

Name
dTDP-4-oxo-alpha-D-xylose hydro-lyase (dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene-forming)
Definition
dTDP-4-oxo-alpha-D-xylose <=> dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + H2O
Equation
Reaction class
RC01448  C21351_C21352
Enzyme
4.2.1.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K21333  dTDP-4-oxo-alpha-D-xylose 2,3-dehydratase [EC:4.2.1.-]

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