KEGG   ORTHOLOGY: K21335Help
Entry
K21335                      KO                                     

Name
calS10, atmS10
Definition
dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase [EC:2.1.1.-]
Pathway
ko00523  Polyketide sugar unit biosynthesis
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K21335  calS10, atmS10; dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-  
     K21335  calS10, atmS10; dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase
BRITE hierarchy
Other DBs
RN: R11476
Genes
SAQ: Sare_2049
AG: AAM70334(calS10) ABC02787(atmS10)
TaxonomyKoalaUniProt
Reference
  Authors
Peltier-Pain P, Singh S, Thorson JS
  Title
Characterization of Early Enzymes Involved in TDP-Aminodideoxypentose Biosynthesis en Route to Indolocarbazole AT2433.
  Journal
Chembiochem 16:2141-6 (2015)
DOI:10.1002/cbic.201500365
Reference
PMID:12183629 (calS10)
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
PMID:16873021 (atmS10)
  Authors
Gao Q, Zhang C, Blanchard S, Thorson JS
  Title
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus.
  Journal
Chem Biol 13:733-43 (2006)
DOI:10.1016/j.chembiol.2006.05.009
  Sequence

KEGG   REACTION: R11476Help
Entry
R11476                      Reaction                               

Name
S-adenosyl-L-methionine:dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase
Definition
S-Adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-Adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose
Equation
Comment
deduced reaction
Reaction class
RC02262  C21354_C21355
Enzyme
2.1.1.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K21335  dTDP-4-amino-2,4-dideoxy-beta-L-xylose N-methyltransferase [EC:2.1.1.-]

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