KEGG   ORTHOLOGY: K21778Help
Entry
K21778                      KO                                     

Name
pigE
Definition
3-acetyloctanal aminotransferase [EC:2.6.1.-]
Pathway
ko00333  Prodigiosin biosynthesis
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21778  pigE; 3-acetyloctanal aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.-  
     K21778  pigE; 3-acetyloctanal aminotransferase
BRITE hierarchy
Other DBs
RN: R11672
COG: COG4992
Genes
SRR: SerAS9_1749
SRS: SerAS12_1749
SRA: SerAS13_1750
SMW: SMWW4_v1c11000(pigE)
SERF: L085_23050
SERA: Ser39006_020675
SERQ: CWC46_20680
VGA: BSQ33_00975
PRR: AT705_06600
HCH: HCH_06028
AG: CAH55633(pigE)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
Reference
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence

KEGG   REACTION: R11672Help
Entry
R11672                      Reaction                               

Definition
(S)-3-Acetyloctanal + Amino acid <=> 2-Methyl-3-n-amyl-dihydropyrrole + 2-Oxo acid
Equation
Comment
aminotransferase
Enzyme
2.6.1.-
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
Orthology
K21778  3-acetyloctanal aminotransferase [EC:2.6.1.-]

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