KEGG   ORTHOLOGY: K21778
Entry
K21778                      KO                                     

Name
pigE
Definition
3-acetyloctanal aminotransferase [EC:2.6.1.-]
Pathway
ko00333  Prodigiosin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21778  pigE; 3-acetyloctanal aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.-  
     K21778  pigE; 3-acetyloctanal aminotransferase
Other DBs
RN: R11672
COG: COG4992
Genes
SMW: SMWW4_v1c11000(pigE)
SRR: SerAS9_1749
SRS: SerAS12_1749
SRA: SerAS13_1750
SERF: L085_23050
SERA: Ser39006_020675
SERQ: CWC46_20680
SERM: CLM71_22590
SSUR: ATE40_002215
VGA: BSQ33_00975
HCH: HCH_06028
AG: CAH55633(pigE)
 » show all
Reference
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
Reference
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence

KEGG   REACTION: R11672
Entry
R11672                      Reaction                               

Definition
(S)-3-Acetyloctanal + Amino acid <=> 2-Methyl-3-n-amyl-dihydropyrrole + 2-Oxo acid
Equation
Comment
aminotransferase
Enzyme
2.6.1.-
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
Orthology
K21778  3-acetyloctanal aminotransferase [EC:2.6.1.-]

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