KEGG   ORTHOLOGY: K21784Help
Entry
K21784                      KO                                     

Name
pigH, redN
Definition
4-hydroxy-2,2'-bipyrrole-5-methanol synthase
Pathway
ko00333  Prodigiosin biosynthesis
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21784  pigH, redN; 4-hydroxy-2,2'-bipyrrole-5-methanol synthase
BRITE hierarchy
Other DBs
RN: R11667
COG: COG0156 COG0236
Genes
SRR: SerAS9_1746
SRS: SerAS12_1746
SRA: SerAS13_1747
SMW: SMWW4_v1c10970(pigH)
SERF: L085_23065
SERA: Ser39006_020660
SERQ: CWC46_20665
SERM: CLM71_22575
VGA: BSQ33_00990
PRR: AT705_06615
HCH: HCH_06031
SCO: SCO5890(redN)
STRD: NI25_09780
AG: CAH55636(pigH)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
Reference
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence

KEGG   REACTION: R11667Help
Entry
R11667                      Reaction                               

Definition
Pyrrolyl-2-carboxyl-S-[acyl-carrier protein] + Malonyl-CoA + L-Serine <=> 4-Hydroxy-2,2'-bipyrrole-5-methanol + CoA + Acyl-carrier protein + 2 CO2 + H2O
Equation
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Orthology
K21784  4-hydroxy-2,2'-bipyrrole-5-methanol synthase

DBGET integrated database retrieval system