KEGG   ORTHOLOGY: K21786
Entry
K21786                      KO                                     

Name
pigF, redI
Definition
4-hydroxy-2,2'-bipyrrole-5-carbaldehyde O-methyltransferase [EC:2.1.1.-]
Pathway
ko00333  Prodigiosin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21786  pigF, redI; 4-hydroxy-2,2'-bipyrrole-5-carbaldehyde O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-  
     K21786  pigF, redI; 4-hydroxy-2,2'-bipyrrole-5-carbaldehyde O-methyltransferase
Other DBs
RN: R11670
Genes
SMW: SMWW4_v1c10990(pigF)
SRR: SerAS9_1748
SRS: SerAS12_1748
SRA: SerAS13_1749
SERF: L085_23055
SERA: Ser39006_020670
SERQ: CWC46_20675
SERM: CLM71_22585
SSUR: ATE40_002210
VGA: BSQ33_00980
HCH: HCH_06029
SCO: SCO5895(redI)
STRD: NI25_09755
AG: CAH55634(pigF)
 » show all
Reference
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
Reference
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence

KEGG   REACTION: R11670
Entry
R11670                      Reaction                               

Name
S-adenosyl-L-methionine:4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde 4-O-methyltransferase
Definition
4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-methionine <=> 4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + S-Adenosyl-L-homocysteine
Equation
Reaction class
RC00392  C21569_C21570
Enzyme
2.1.1.-
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Orthology
K21786  4-hydroxy-2,2'-bipyrrole-5-carbaldehyde O-methyltransferase [EC:2.1.1.-]

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