KEGG   ORTHOLOGY: K21787Help
Entry
K21787                      KO                                     

Name
pigC, redH
Definition
prodigiosin/undecylprodigiosin synthetase
Pathway
ko00333  Prodigiosin biosynthesis
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00333 Prodigiosin biosynthesis
    K21787  pigC, redH; prodigiosin/undecylprodigiosin synthetase
BRITE hierarchy
Other DBs
RN: R11662 R11673
COG: COG0574
Genes
SRR: SerAS9_1751
SRS: SerAS12_1751
SRA: SerAS13_1752
SMW: SMWW4_v1c11020(pigC)
SERF: L085_23040
SERA: Ser39006_020685
SERQ: CWC46_20690
SERM: CLM71_22600
VGA: BSQ33_00965
PRR: AT705_06590
HCH: HCH_06026
SCO: SCO5896(redH)
STRD: NI25_09750
SALF: SMD44_07458(pps)
AG: CAH55631(pigC)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
  Sequence
Reference
  Authors
Harris AK, Williamson NR, Slater H, Cox A, Abbasi S, Foulds I, Simonsen HT, Leeper FJ, Salmond GP
  Title
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation.
  Journal
Microbiology 150:3547-60 (2004)
DOI:10.1099/mic.0.27222-0
  Sequence

KEGG   REACTION: R11673Help
Entry
R11673                      Reaction                               

Definition
4-Methoxy-2,2'-bipyrrole-5-carbaldehyde + 2-Undecylpyrrole + ATP <=> Undecylprodigiosin + ADP + Orthophosphate
Equation
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Orthology
K21787  prodigiosin/undecylprodigiosin synthetase

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