KEGG   ORTHOLOGY: K22099
Entry
K22099                      KO                                     

Name
folC2
Definition
dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Pathway
ko00790  Folate biosynthesis
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
Module
M00840  Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K22099  folC2; dihydrofolate synthase / folylpolyglutamate synthase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     K22099  folC2; dihydrofolate synthase / folylpolyglutamate synthase
    6.3.2.17  tetrahydrofolate synthase
     K22099  folC2; dihydrofolate synthase / folylpolyglutamate synthase
Other DBs
RN: R00942 R02237 R04241
COG: COG1478
GO: 0008841 0004326
Genes
WRI: WRi_008600
WEN: wHa_07620
WOO: wOo_06860
WCL: WCLE_011760
NAF: GQ61_00350
BBA: Bd1262
BBAT: Bdt_1245
BBW: BDW_04340
BBAC: EP01_16245
BDC: DOE51_01850
CTR: CT_611
CTA: CTA_0664
CTY: CTR_6151
CRA: CTO_0664
CTRQ: A363_00656
CTB: CTL0875
CTO: CTL2C_438
CTJ: JALI_6151
CTZ: CTB_6151
CSW: SW2_6221
CES: ESW3_6221
CTRB: BOUR_00651
CTEC: EC599_6331
CFS: FSW4_6221
CFW: FSW5_6221
CTFW: SWFP_6601
CTCH: O173_03355
CTRI: BN197_6201
CTRA: BN442_6201
CTCT: CTW3_03370
CMU: TC_0901
CMUR: Y015_04775
CMX: DNC_04580
CMZ: TAC_04775
CPN: CPn0760
CPA: CP_1112
CPJ: CPj0760(CPj0760)
CPT: CpB0788
CHB: G5O_1049
CHR: Cpsi_9831
CPSC: B711_1139
CPSN: B712_1069
CPSB: B595_1144
CPSG: B598_1068
CPSM: B602_1072
CPSI: B599_1066
CPSV: B600_1139
CPSW: B603_1075
CPST: B601_1074
CPSD: BN356_9871
CPSA: AO9_05125
CCA: CCA_00997
CAB: CAB967
CABO: AB7_10631
CFE: CF0016(oxr1)
CHLA: C834K_1027
EMI: Emin_0056
 » show all
Reference
  Authors
Adams NE, Thiaville JJ, Proestos J, Juarez-Vazquez AL, McCoy AJ, Barona-Gomez F, Iwata-Reuyl D, de Crecy-Lagard V, Maurelli AT
  Title
Promiscuous and adaptable enzymes fill "holes" in the tetrahydrofolate pathway in Chlamydia species.
  Journal
MBio 5:e01378-14 (2014)
DOI:10.1128/mBio.01378-14
Reference
PMID:9784136
  Authors
Stephens RS, Kalman S, Lammel C, Fan J, Marathe R, Aravind L, Mitchell W, Olinger L, Tatusov RL, Zhao Q, Koonin EV, Davis RW.
  Title
Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis.
  Journal
Science 282:754-9 (1998)
DOI:10.1126/science.282.5389.754
  Sequence
[ctr:CT_611]

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