KEGG   ORTHOLOGY: K22275Help
Entry
K22275                      KO                                     

Name
NS5A
Definition
HCV non-structural protein 5A
Pathway
ko05160  Hepatitis C
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K22275  NS5A; HCV non-structural protein 5A
  09172 Infectious disease: viral
   05160 Hepatitis C
    K22275  NS5A; HCV non-structural protein 5A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03200 Viral proteins
    K22275  NS5A; HCV non-structural protein 5A
Viral proteins [BR:ko03200]
 +ssRNA viruses
  Hepatitis C virus
   K22275  NS5A; HCV non-structural protein 5A
BRITE hierarchy
Genes
AG: NP_751927(NS5A)
TaxonomyKoalaUniProt
Reference
  Authors
Badillo A, Receveur-Brechot V, Sarrazin S, Cantrelle FX, Delolme F, Fogeron ML, Molle J, Montserret R, Bockmann A, Bartenschlager R, Lohmann V, Lippens G, Ricard-Blum S, Hanoulle X, Penin F
  Title
Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A.
  Journal
Biochemistry 56:3029-3048 (2017)
DOI:10.1021/acs.biochem.7b00212
  Sequence
Reference
  Authors
Scheel TK, Rice CM
  Title
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies.
  Journal
Nat Med 19:837-49 (2013)
DOI:10.1038/nm.3248

DBGET integrated database retrieval system