KEGG   ORTHOLOGY: K22392
Entry
K22392            Tight     KO                                     
Symbol
hppE
Name
(S)-2-hydroxypropylphosphonic acid epoxidase [EC:1.11.1.23]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R08863  (S)-2-hydroxypropylphosphonate,NADH:oxygen epoxidase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K22392  hppE; (S)-2-hydroxypropylphosphonic acid epoxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.23  (S)-2-hydroxypropylphosphonic acid epoxidase
     K22392  hppE; (S)-2-hydroxypropylphosphonic acid epoxidase
Genes
AG: BAA94418(hppE)
Reference
PMID:18656958
  Authors
Munos JW, Moon SJ, Mansoorabadi SO, Chang W, Hong L, Yan F, Liu A, Liu HW
  Title
Purification and characterization of the epoxidase catalyzing the formation of fosfomycin from Pseudomonas syringae.
  Journal
Biochemistry 47:8726-35 (2008)
DOI:10.1021/bi800877v
  Sequence
[ag:BAA94418]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1)   
   KEGG GENES (1)   
Literature (1)   
   PubMed (1)   
All databases (13)   

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KEGG   ORTHOLOGY: K12903
Entry
K12903            Tight     KO                                     
Symbol
fom4
Name
(S)-2-hydroxypropylphosphonic acid epoxidase [EC:1.11.1.23]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Reaction
R08863  (S)-2-hydroxypropylphosphonate,NADH:oxygen epoxidase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K12903  fom4; (S)-2-hydroxypropylphosphonic acid epoxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.23  (S)-2-hydroxypropylphosphonic acid epoxidase
     K12903  fom4; (S)-2-hydroxypropylphosphonic acid epoxidase
Genes
AG: BAA32491(fom4)
Reference
PMID:19489722
  Authors
Metcalf WW, van der Donk WA
  Title
Biosynthesis of phosphonic and phosphinic acid natural products.
  Journal
Annu Rev Biochem 78:65-94 (2009)
DOI:10.1146/annurev.biochem.78.091707.100215
Reference
PMID:7500951
  Authors
Hidaka T, Goda M, Kuzuyama T, Takei N, Hidaka M, Seto H
  Title
Cloning and nucleotide sequence of fosfomycin biosynthetic genes of Streptomyces wedmorensis.
  Journal
Mol Gen Genet 249:274-80 (1995)
DOI:10.1007/BF00290527
  Sequence
[ag:BAA32491]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1)   
   KEGG GENES (1)   
Literature (2)   
   PubMed (2)   
All databases (15)   

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