KEGG   ORTHOLOGY: K23125
Entry
K23125                      KO                                     

Name
DEFB1
Definition
beta-defensin 1
Pathway
ko02010  ABC transporters
ko05150  Staphylococcus aureus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K23125  DEFB1; beta-defensin 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K23125  DEFB1; beta-defensin 1
Other DBs
GO: 0031731
TC: 1.C.85.1.1 1.C.85.1.9
Genes
HSA: 1672(DEFB1)
PTR: 450100(DEFB1)
PPS: 100979165(DEFB1)
GGO: 101148919(DEFB1)
PON: 100460518(DEFB1)
NLE: 100592794(DEFB1)
MCC: 574187(DEFB1)
MCF: 102147207(DEFB1)
CSAB: 103215297(DEFB1)
RRO: 104676536(DEFB1)
RBB: 108516725(DEFB1)
CJC: 100406393(DEFB1)
MMU: 13214(Defb1)
RNO: 83687(Defb1)
MUN: 110541340(Defb1)
CGE: 103161655(Defb1)
NGI: 103745283(Defb1)
HGL: 101713234(Defb1)
CCAN: 109702617(Defb1)
OCU: 103352242(DEFB1)
TUP: 102499596(DEFB1)
CFA: 611241(DEFB1)
VVP: 112934486(DEFB1)
AML: 100467200(DEFB1)
UMR: 103676928(DEFB1)
UAH: 113262187(DEFB1)
ORO: 101367768(DEFB1)
ELK: 111144381
FCA: 102902220(DEFB1)
PTG: 102954572(DEFB1)
PPAD: 109260743(DEFB1)
AJU: 106982003(DEFB1)
SSC: 404699(DEFB1)
CFR: 102512176(DEFB1)
CDK: 105084407(DEFB1)
BACU: 103006724
LVE: 103076504
OOR: 105748584(DEFB1)
DLE: 111173350(DEFB1)
PCAD: 102983732(DEFB1)
ECB: 102150198(DEFB1)
EPZ: 103557227(DEFB1)
EAI: 106841422(DEFB1)
DRO: 112321317(DEFB1)
RAY: 107504267(DEFB1)
MJV: 108410142(DEFB1)
MDO: 103105417
OAA: 114806550(DEFB1)
MGP: 116216384(DEFB1)
NMEL: 110396741(DEFB1)
APLA: 110351731
FCH: 114017036
NNI: 104014754(DEFB1)
ACUN: 113478901(DEFB1)
PMUR: 107293176
XTR: 116411106
 » show all
Reference
PMID:9268634
  Authors
Liu L, Zhao C, Heng HH, Ganz T
  Title
The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.
  Journal
Genomics 43:316-20 (1997)
DOI:10.1006/geno.1997.4801
  Sequence
[hsa:1672]

KEGG   ORTHOLOGY: K21100
Entry
K21100                      KO                                     

Name
DEFB4
Definition
beta-defensin 4
Pathway
ko04621  NOD-like receptor signaling pathway
ko04657  IL-17 signaling pathway
ko05150  Staphylococcus aureus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K21100  DEFB4; beta-defensin 4
   04657 IL-17 signaling pathway
    K21100  DEFB4; beta-defensin 4
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K21100  DEFB4; beta-defensin 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K21100  DEFB4; beta-defensin 4
Transporters [BR:ko02000]
 Other transporters
  Pores ion channels
   K21100  DEFB4; beta-defensin 4
Other DBs
GO: 0031731
TC: 1.C.85.1.2
Genes
HSA: 100289462(DEFB4B) 1673(DEFB4A)
PTR: 450193(DEFB4A)
GGO: 115930144
PON: 100436028
NLE: 100604016
MCC: 100169969(DEFB4) 114675435 114675439 114676064 114680396
MCF: 102124095 107130570
CSAB: 103215308(DEFB4B)
RRO: 104675523
RBB: 108539813
CJC: 103787421(DEFB4B)
SBQ: 101047470
MMU: 56519(Defb4)
RNO: 64389(Defb4)
MUN: 110566871
CGE: 100767221
NGI: 103740473
CFA: 100135059(DEFB4A)
BTA: 100141457(DEFB10) 100297617(DEFB1) 281743(EBD) 286837(TAP)
CHX: 100861169(GBD) 100861170(BD-1)
OAS: 100505451(SBD2)
SSC: 396819(DEFB1)
ECB: 100033989(DEFB4B)
GGA: 395840(AvBD2)
MGP: 678665(THP2)
CJO: 107312329
NMEL: 110396689
APLA: 101795872(BD2) 110354225
TGU: 101233915
SCAN: 103823292
GFR: 102045191
FAB: 101814600
PHI: 102107437
PMAJ: 107201203
CLV: 102084061
EGZ: 104127275
NNI: 104014755(DEFB4B)
ACUN: 113478331
AAM: 106494616
ACS: 100555370 100861406(bd27)
PVT: 110070259
PMUA: 114593373
 » show all
Reference
PMID:9831658
  Authors
Liu L, Wang L, Jia HP, Zhao C, Heng HH, Schutte BC, McCray PB Jr, Ganz T
  Title
Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation.
  Journal
Gene 222:237-44 (1998)
DOI:10.1016/S0378-1119(98)00480-6
  Sequence
[hsa:1673]

KEGG   ORTHOLOGY: K23126
Entry
K23126                      KO                                     

Name
DEFB103
Definition
beta-defensin 103
Pathway
ko04621  NOD-like receptor signaling pathway
ko05150  Staphylococcus aureus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K23126  DEFB103; beta-defensin 103
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K23126  DEFB103; beta-defensin 103
Other DBs
TC: 1.C.85.1.3
Genes
HSA: 414325(DEFB103A) 55894(DEFB103B)
PTR: 450106(DEFB103A)
GGO: 101125223
PON: 100435661
NLE: 100596700 115833672
MCC: 694235
MCF: 102119017
CSAB: 103215309
RRO: 104675522
RBB: 108539805
CJC: 100407484(DEFB103B)
SBQ: 101047788
MMU: 244332(Defb14)
MCAL: 110300690
RNO: 641627(Defb14)
MUN: 110566872
CGE: 100769521
NGI: 103738860
HGL: 101704958
CCAN: 109674519
OCU: 108175984
TUP: 102491530
CFA: 100170103(CBD103)
VVP: 112934480
AML: 100465205
UMR: 103676927
UAH: 113262043(DEFB103A)
ORO: 101368637(DEFB4B)
ELK: 111144388
FCA: 101101212
PTG: 102953810(DEFB4B)
PPAD: 109260741
AJU: 106981998
BBUB: 102414555
CHX: 102188015
OAS: 101105214
SSC: 404703
CFR: 106728844
CDK: 116149219
DLE: 111173353
PCAD: 112062148
ECB: 100629456
EPZ: 103544921
EAI: 106841389(DEFB4B)
MYB: 102243238
MYD: 102751341
MNA: 107541945
HAI: 109386810
DRO: 112321316
PALE: 102878155
RAY: 107504272(DEFB4B)
MJV: 108410135
LAV: 111751269
TMU: 111821580
MDO: 100032666
SHR: 100919991
PCW: 110207513
OAA: 114807414
LSR: 116183449
PMAJ: 107201193
CCAE: 111942670
ETL: 114069922
FCH: 114016484
ACUN: 113478881
PSS: 102450934
PVT: 110071134
PBI: 103061251
TSR: 106538153
CMK: 103187030
 » show all
Reference
  Authors
Harder J, Bartels J, Christophers E, Schroder JM
  Title
Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.
  Journal
J Biol Chem 276:5707-13 (2001)
DOI:10.1074/jbc.M008557200
  Sequence

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