KEGG   ORTHOLOGY: K23891
Entry
K23891            Tight     KO                                     

Name
ROQN
Definition
glandicoline B O-methyltransferase [EC:2.1.1.-]
Pathway
ko00404  Staurosporine biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K23891  ROQN; glandicoline B O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-  
     K23891  ROQN; glandicoline B O-methyltransferase
Other DBs
RN: R12443 R12447
Genes
PCS: Pc21g15440
Reference
  Authors
Ali H, Ries MI, Nijland JG, Lankhorst PP, Hankemeier T, Bovenberg RA, Vreeken RJ, Driessen AJ
  Title
A branched biosynthetic pathway is involved in production of roquefortine and related compounds in Penicillium chrysogenum.
  Journal
PLoS One 8:e65328 (2013)
DOI:10.1371/journal.pone.0065328
  Sequence
Reference
  Authors
Ries MI, Ali H, Lankhorst PP, Hankemeier T, Bovenberg RA, Driessen AJ, Vreeken RJ
  Title
Novel key metabolites reveal further branching of the roquefortine/meleagrin biosynthetic pathway.
  Journal
J Biol Chem 288:37289-95 (2013)
DOI:10.1074/jbc.M113.512665
  Sequence

KEGG   REACTION: R12447
Entry
R12447                      Reaction                               

Definition
N1-Hydroxy-roquefortine C + S-Adenosyl-L-methionine <=> Roquefortine F + S-Adenosyl-L-homocysteine
Equation
Comment
N1-Hydroxy-roquefortine C O-methyltransferase
Reaction class
RC03543  C22169_C22171
Enzyme
2.1.1.-
Pathway
rn00404  Staurosporine biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K23891  glandicoline B O-methyltransferase [EC:2.1.1.-]

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