KEGG   ORTHOLOGY: K24439
Entry
K24439                      KO                                     

Name
STCL, CYP60B1
Definition
versicolorin B desaturase [EC:1.14.-.-]
Pathway
ko00254  Aflatoxin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00937  Aflatoxin biosynthesis, malonyl-CoA => aflatoxin B1
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    K24439  STCL, CYP60B1; versicolorin B desaturase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K24439  STCL, CYP60B1; versicolorin B desaturase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
    1.14.-.-  
     K24439  STCL, CYP60B1; versicolorin B desaturase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP60 family
   K24439  STCL, CYP60B1; versicolorin B desaturase
Other DBs
RN: R10479
COG: COG2124
Genes
PAN: PODANSg8558
ANI: AN7813.2
AOR: AO090026000022
AFV: AFLA_139250
Reference
PMID:8999832
  Authors
Kelkar HS, Skloss TW, Haw JF, Keller NP, Adams TH
  Title
Aspergillus nidulans stcL encodes a putative cytochrome P-450 monooxygenase required for bisfuran desaturation during aflatoxin/sterigmatocystin biosynthesis.
  Journal
J Biol Chem 272:1589-94 (1997)
DOI:10.1074/jbc.272.3.1589
  Sequence
[ani:AN7813.2]
Reference
  Authors
Kelly DE, Krasevec N, Mullins J, Nelson DR
  Title
The CYPome (Cytochrome P450 complement) of Aspergillus nidulans.
  Journal
Fungal Genet Biol 46 Suppl 1:S53-61 (2009)
DOI:10.1016/j.fgb.2008.08.010

KEGG   REACTION: R10479
Entry
R10479                      Reaction                               

Definition
Versicolorin B + Oxygen + NADPH + H+ <=> Versicolorin A + NADP+ + 2 H2O
Equation
Comment
versicolorin B desaturase
Reaction class
RC00001  C00005_C00006
RC03162  C20575_C20583
Pathway
rn00254  Aflatoxin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00937  Aflatoxin biosynthesis, malonyl-CoA => aflatoxin B1
Orthology
K24439  versicolorin B desaturase [EC:1.14.-.-]
Other DBs
RHEA: 35746

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