KEGG   ORTHOLOGY: K24855
Entry
K24855                      KO                                     

Name
STCW
Definition
hydroxyversicolorone monooxygenase [EC:1.14.13.-]
Pathway
ko00254  Aflatoxin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00937  Aflatoxin biosynthesis, malonyl-CoA => aflatoxin B1
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    K24855  STCW; hydroxyversicolorone monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-  
     K24855  STCW; hydroxyversicolorone monooxygenase
Other DBs
RN: R10477 R10478
COG: COG2072
Genes
QSU: 112011408
PAN: PODANSg8551
SAPO: SAPIO_CDS8254
PFY: PFICI_02449
SSL: SS1G_05124
BFU: BCIN_09g01960
PSCO: LY89DRAFT_635545
ANI: AN7804.2
AOR: AO090026000030
AFV: AFLA_139170
 » show all
Reference
  Authors
Keller NP, Watanabe CM, Kelkar HS, Adams TH, Townsend CA
  Title
Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans.
  Journal
Appl Environ Microbiol 66:359-62 (2000)
DOI:10.1128/aem.66.1.359-362.2000
  Sequence
[ani:AN7804.2]
Reference
  Authors
Yu J, Chang PK, Bhatnagar D, Cleveland TE
  Title
Genes encoding cytochrome P450 and monooxygenase enzymes define one end of the aflatoxin pathway gene cluster in Aspergillus parasiticus.
  Journal
Appl Microbiol Biotechnol 53:583-90 (2000)
DOI:10.1007/s002530051660
  Sequence
Reference
  Authors
Wen Y, Hatabayashi H, Arai H, Kitamoto HK, Yabe K.
  Title
Function of the cypX and moxY genes in aflatoxin biosynthesis in Aspergillus parasiticus.
  Journal
Appl Environ Microbiol 71:3192-8 (2005)

KEGG   REACTION: R10477
Entry
R10477                      Reaction                               

Definition
1'-Hydroxyversicolorone + NADPH + H+ + Oxygen <=> Versiconal hemiacetal acetate + NADP+ + H2O
Equation
Comment
versiconal hemiacetal acetate synthase
Reaction class
RC00001  C00005_C00006
RC03159  C20503_C20505
Pathway
rn00254  Aflatoxin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00937  Aflatoxin biosynthesis, malonyl-CoA => aflatoxin B1
Orthology
K24855  hydroxyversicolorone monooxygenase [EC:1.14.13.-]

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