KEGG   MODULE: M00061
Entry
M00061            Pathway   Module                                 

Name
D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P
Definition
K01812 K00040 (K01686,K08323) K00874 (K01625,K17463)
Diagram
M00061

Orthology
K01812  
glucuronate isomerase [EC:5.3.1.12] [RN:R01482]
K00040  
fructuronate reductase [EC:1.1.1.57] [RN:R02454]
mannonate dehydratase [EC:4.2.1.8] [RN:R05606]
K00874  
2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] [RN:R01541]
2-dehydro-3-deoxy-phosphogluconate aldolase [EC:4.1.2.14] [RN:R05605]
Class
Pathway modules; Carbohydrate metabolism; Other carbohydrate metabolism
Pathway
map00040  Pentose and glucuronate interconversions
map00030  Pentose phosphate pathway
map01100  Metabolic pathways
Reaction
Compound
C00191  D-Glucuronate
C00905  D-Fructuronate
C00514  D-Mannonate
C00204  2-Dehydro-3-deoxy-D-gluconate
C04442  2-Dehydro-3-deoxy-6-phospho-D-gluconate
C00022  Pyruvate
C00118  D-Glyceraldehyde 3-phosphate
Reference
  Authors
ASHWELL G, WAHBA AJ, HICKMAN J
  Title
Uronic acid metabolism in bacteria. I. Purification and properties of uronic acid isomerase in Escherichia coli.
  Journal
J Biol Chem 235:1559-65 (1960)

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