KEGG   MODULE: M00114
Entry
M00114            Pathway   Module                                 

Name
Ascorbate biosynthesis, plants, fructose-6P => ascorbate
Definition
K01809 K17497 K00966 K10046 K14190 K10047 K17744 K00225
Diagram
M00114

Orthology
K01809  
mannose-6-phosphate isomerase [EC:5.3.1.8] [RN:R01819]
K17497  
phosphomannomutase [EC:5.4.2.8] [RN:R01818]
K00966  
mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] [RN:R00885]
K10046  
GDP-D-mannose 3', 5'-epimerase [EC:5.1.3.18] [RN:R00889]
K14190  
GDP-L-galactose phosphorylase [EC:2.7.7.69] [RN:R07678]
K10047  
L-galactose 1-phosphate phosphatase [EC:3.1.3.93] [RN:R07674]
K17744  
L-galactose dehydrogenase [EC:1.1.1.316] [RN:R07675]
K00225  
L-galactono-1,4-lactone dehydorogenase [EC:1.3.2.3] [RN:R00640]
Class
Pathway modules; Carbohydrate metabolism; Other carbohydrate metabolism
Pathway
map00051  Fructose and mannose metabolism
map00053  Ascorbate and aldarate metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
Compound
C05345  beta-D-Fructose 6-phosphate
C00275  D-Mannose 6-phosphate
C00636  D-Mannose 1-phosphate
C00096  GDP-mannose
C02280  GDP-L-galactose
C15926  beta-L-Galactose 1-phosphate
C01825  L-Galactose
C01115  L-Galactono-1,4-lactone
C00072  Ascorbate
Reference
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200

  All links  
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (17)   
   KEGG ENZYME (9)   
   KEGG REACTION (8)   
Gene (8)   
   KEGG ORTHOLOGY (8)   
Literature (1)   
   PubMed (1)   
All databases (40)   

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