KEGG   MODULE: M00128
Entry
M00128            Pathway   Module                                 
Name
Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol
Definition
K06125 K06126 K00591 -- -- K06127 K06134 K00591
Diagram
M00128

Orthology
K06125  
COQ2; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] [RN:R05000]
K06126  
COQ6; ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-] [RN:R08770]
K00591  
COQ3; polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase [EC:2.1.1.114 2.1.1.64] [RN:R08771 R12657]
K06127  
COQ5; 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.201] [RN:R09737]
K06134  
COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60] [RN:R12067]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
R05000  
R08770  
R08771  
R08772  
R12658  
R09737  
R12067  
R12657  
Compound
C00156  4-Hydroxybenzoate
C05847  all-trans-Polyprenyl diphosphate
C05848  4-Hydroxy-3-polyprenylbenzoate
C17554  3,4-Dihydroxy-5-polyprenylbenzoate
C17559  3-Methoxy-4-hydroxy-5-polyprenylbenzoate
C17552  2-Polyprenyl-6-methoxyphenol
C19858  2-Methoxy-6-all-trans-polyprenyl-1,4-benzoquinol
C19859  6-Methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol
C21860  3-Demethylubiquinol
C00390  Ubiquinol
Reference
PMID:26183239
  Authors
Kawamukai M
  Title
Biosynthesis of coenzyme Q in eukaryotes.
  Journal
Biosci Biotechnol Biochem 80:23-33 (2016)
DOI:10.1080/09168451.2015.1065172

  All links  
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (13)   
   KEGG ENZYME (5)   
   KEGG REACTION (8)   
Gene (5)   
   KEGG ORTHOLOGY (5)   
Literature (1)   
   PubMed (1)   
All databases (32)   

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