KEGG   MODULE: M00358
Entry
M00358            Pathway   Module                                 

Name
Coenzyme M biosynthesis
Definition
K08097 K05979 K05884 K13039+K06034
Diagram
M00358

Orthology
K08097  
phosphosulfolactate synthase [EC:4.4.1.19] [RN:R07476]
K05979  
2-phosphosulfolactate phosphatase [EC:3.1.3.71] [RN:R05789]
K05884  
L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337] [RN:R07136]
sulfopyruvate decarboxylase [EC:4.1.1.79] [RN:R05774]
Class
Pathway modules; Energy metabolism; Methane metabolism
Pathway
map00680  Methane metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
Compound
C00074  Phosphoenolpyruvate
C11536  (2R)-O-Phospho-3-sulfolactate
C11537  (2R)-3-Sulfolactate
C05528  3-Sulfopyruvate
C00593  Sulfoacetaldehyde
C03576  2-Mercaptoethanesulfonate
Reference
  Authors
Graham DE, Xu H, White RH
  Title
Identification of coenzyme M biosynthetic phosphosulfolactate synthase: a new family of sulfonate-biosynthesizing enzymes.
  Journal
J Biol Chem 277:13421-9 (2002)
DOI:10.1074/jbc.M201011200

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