KEGG   MODULE: M00786
Entry
M00786            Pathway   Module                                 

Name
Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A
Definition
K18281 K14132 K17475 K18280 K17827 K17826 K14134 K17825 K18279
Diagram
M00786

Orthology
K18281  
FTMA; brevianamide F synthase [RN:R10661]
K14132  
FTMPT1; tryprostatin B synthase [EC:2.5.1.106] [RN:R10340]
K17475  
FTMC; tryprostatin B 6-hydroxylase [EC:1.14.14.118] [RN:R10321]
K18280  
FTMD; 6-hydroxytryprostatin B O-methyltransferase [EC:2.1.1.293] [RN:R10588]
K17827  
FTME; fumitremorgin C synthase [EC:1.14.19.71] [RN:R10416]
K17826  
FTMG; fumitremorgin C monooxygenase [EC:1.14.14.119] [RN:R10414]
K14134  
FTMPT2; 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase [EC:2.5.1.110] [RN:R10457]
K17825  
FTMF; verruculogen synthase [EC:1.14.11.38] [RN:R10445]
K18279  
FTMPT3; verruculogen prenyltransferase [EC:2.5.1.107] [RN:R10341]
Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other fungal compounds
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
Compound
C00078  L-Tryptophan
C00148  L-Proline
C20563  Brevianamide F
C20512  Tryprostatin B
C20513  6-Hydroxytryprostatin B
C20607  Tryprostatin A
C20604  Fumitremorgin C
C20605  12alpha,13alpha-Dihydroxyfumitremorgin C
C20630  Fumitremorgin B
C20045  Verruculogen
C20564  Fumitremorgin A

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