KEGG   MODULE: M00808
Entry
M00808            Pathway   Module                                 

Name
Violacein biosynthesis, tryptophan => violacein
Definition
K20086 K20087+K20088 K20089 K20090
Diagram
M00808

Orthology
K20086  
vioA; tryptophan oxidase VioA [EC:1.4.3.-] [RN:R11119]
K20087  
vioB; violacein biosynthesis protein VioB [RN:R11131]
K20088  
vioE; violacein biosynthesis protein VioE [RN:R11131]
K20089  
vioD; flavin-dependent oxygenase VioD [EC:1.14.13.-] [RN:R11134]
K20090  
vioC; flavin-dependent oxygenase VioC [EC:1.14.13.-] [RN:R11135]
Class
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other bacterial compounds
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
Compound
C00078  L-Tryptophan
C21124  IPA imine
C21131  Protodeoxyviolaceinic acid
C21134  Protoviolaceinic acid
C21135  Violaceinic acid
C21136  Violacein
Reference
  Authors
Lee ME, Aswani A, Han AS, Tomlin CJ, Dueber JE
  Title
Expression-level optimization of a multi-enzyme pathway in the absence of a high-throughput assay.
  Journal
Nucleic Acids Res 41:10668-78 (2013)
DOI:10.1093/nar/gkt809

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