KEGG   MODULE: M00872
Entry
M00872            Pathway   Module                                 

Name
O-glycan biosynthesis, mannose type (core M3)
Definition
K00728 K18207 K09654 K17547
K21031
K19872 K19873 K21052 K21032 K09668
Diagram
M00872

Orthology
K00728  
POMT; dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] [RN:R07620]
K18207  
POMGNT2; protein O-mannose beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.312] [RN:R11407]
K09654  
B3GALNT2; beta-1,3-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.313] [RN:R12292]
K17547  
POMK; glycoprotein-mannosyl O6-kinase [EC:2.7.1.183] [RN:R12293]
K21031  
ISPD; D-ribitol-5-phosphate cytidylyltransferase [EC:2.7.7.40] [RN:R02921]
K19872  
FKTN; fukutin [EC:2.7.8.-] [RN:R12294]
K19873  
FKRP; fukutin-related protein [EC:2.7.8.-] [RN:R12295]
K21052  
TMEM5; alpha-dystroglycan beta1,4-xylosyltransferase [EC:2.4.2.61] [RN:R12244]
K21032  
B4GAT1; beta-1,4-glucuronyltransferase 1 [EC:2.4.1.-] [RN:R12296]
K09668  
LARGE; glycosyltransferase-like protein LARGE [EC:2.4.2.- 2.4.1.-] [RN:R12297 R12298]
Class
Pathway modules; Glycan metabolism; Glycan biosynthesis
Pathway
map00515  Mannose type O-glycan biosynthesis
map01100  Metabolic pathways
Reaction
Compound
G10617  Dolichyl phosphate D-mannose
C02189  [Protein]-L-serine
G13027   
G13087   
G13091  O-mannose core M3
G13092  Phospho-core M3
C00063  CTP
C01068  D-Ribitol 5-phosphate
C00789  CDP-ribitol
G13093   
G13094   
G13095   
G13096   
G13097   
G13098   
Reference
  Authors
Endo T
  Title
Mammalian O-mannosyl glycans: Biochemistry and glycopathology.
  Journal
Proc Jpn Acad Ser B Phys Biol Sci 95:39-51 (2019)
DOI:10.2183/pjab.95.004

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