KEGG   MODULE: M00909
Entry
M00909            Pathway   Module                                 

Name
UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc
Definition
K00845 (K01810,K13810,K15916) K00820 K03431 K04042
Diagram
M00909

Orthology
K00845  
glk; glucokinase [EC:2.7.1.2] [RN:R01786]
pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] [RN:R02740]
K00820  
glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] [RN:R00768]
K03431  
glmM; phosphoglucosamine mutase [EC:5.4.2.10] [RN:R02060]
K04042  
glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] [RN:R05332 R00416]
Class
Pathway modules; Carbohydrate metabolism; Other carbohydrate metabolism
Pathway
map00520  Amino sugar and nucleotide sugar metabolism
map01100  Metabolic pathways
Reaction
Compound
C00267  alpha-D-Glucose
C00668  alpha-D-Glucose 6-phosphate
C05345  beta-D-Fructose 6-phosphate
C00352  D-Glucosamine 6-phosphate
C06156  alpha-D-Glucosamine 1-phosphate
C04501  N-Acetyl-alpha-D-glucosamine 1-phosphate
C00043  UDP-N-acetyl-alpha-D-glucosamine
Reference
PMID:8083170
  Authors
Mengin-Lecreulx D, van Heijenoort J
  Title
Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1-phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis.
  Journal
J Bacteriol 176:5788-95 (1994)
DOI:10.1128/jb.176.18.5788-5795.1994
Reference
  Authors
Teplyakov A, Obmolova G, Badet-Denisot MA, Badet B
  Title
The mechanism of sugar phosphate isomerization by glucosamine 6-phosphate synthase.
  Journal
Protein Sci 8:596-602 (1999)
DOI:10.1110/ps.8.3.596

  All links  
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (14)   
   KEGG ENZYME (8)   
   KEGG REACTION (6)   
Gene (7)   
   KEGG ORTHOLOGY (7)   
Literature (2)   
   PubMed (2)   
All databases (32)   

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