KEGG   MODULE: M00935
Entry
M00935            Pathway   Module                                 

Name
Methanofuran biosynthesis
Definition
K09733 K19793 K07144
K18933 K06914
K07072
Diagram
M00935

Orthology
K09733  
mfnB; (5-formylfuran-3-yl)methyl phosphate synthase [EC:4.2.3.153] [RN:R10935]
K19793  
mfnC; (5-formylfuran-3-yl)methyl phosphate transaminase [EC:2.6.1.108] [RN:R11038]
K07144  
mfnE; 5-(aminomethyl)-3-furanmethanol phosphate kinase [EC:2.7.4.31] [RN:R11039]
K18933  
mfnA; tyrosine decarboxylase [EC:4.1.1.25] [RN:R00736]
K06914  
mfnD; tyramine---L-glutamate ligase [EC:6.3.4.24] [RN:R10902]
K07072  
mfnF; (4-(4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl)furan-2-yl)methanamine synthase [EC:2.5.1.131] [RN:R11040]
Class
Pathway modules; Energy metabolism; Methane metabolism
Pathway
map00680  Methane metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
Reaction
Compound
C00118  D-Glyceraldehyde 3-phosphate
C20954  (5-Formylfuran-3-yl)methyl phosphate
C21068  [5-(Aminomethyl)furan-3-yl]methyl phosphate
C21069  [5-(Aminomethyl)furan-3-yl]methyl diphosphate
C00082  L-Tyrosine
C00483  Tyramine
C20926  gamma-Glutamyltyramine
C21070  (4-{4-[2-(gamma-L-Glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine
Reference
  Authors
Kezmarsky ND, Xu H, Graham DE, White RH
  Title
Identification and characterization of a L-tyrosine decarboxylase in Methanocaldococcus jannaschii.
  Journal
Biochim Biophys Acta 1722:175-82 (2005)
DOI:10.1016/j.bbagen.2004.12.003
Reference
  Authors
Wang Y, Xu H, Jones MK, White RH
  Title
Identification of the Final Two Genes Functioning in Methanofuran Biosynthesis in Methanocaldococcus jannaschii.
  Journal
J Bacteriol 197:2850-8 (2015)
DOI:10.1128/JB.00401-15

DBGET integrated database retrieval system