Entry |
|
Name |
HTLV-1 Tax to p21-cell cycle G1/S
|
Definition |
TAX -| CDKN1A -| (CDK2+CCNE) -> RB1 // E2F |
Expanded |
K21857 -| 1026 -| (1017+(898,9134)) -> 5925 // (1869,1870,1871) |
Class |
nt06160 Human T-cell leukemia virus 1 (HTLV-1)
|
Type |
Pathogen
|
Pathway |
hsa05166 | Human T-cell leukemia virus 1 infection |
|
Disease |
|
Gene |
1026 | CDKN1A; cyclin dependent kinase inhibitor 1A |
1017 | CDK2; cyclin dependent kinase 2 |
5925 | RB1; RB transcriptional corepressor 1 |
1869 | E2F1; E2F transcription factor 1 |
1870 | E2F2; E2F transcription factor 2 |
1871 | E2F3; E2F transcription factor 3 |
|
Perturbant |
K21857 (TAX) | tax; HTLV protein Tax-1 |
|
Reference |
|
Authors |
Grassmann R, Aboud M, Jeang KT |
Title |
Molecular mechanisms of cellular transformation by HTLV-1 Tax. |
Journal |
|
Reference |
|
Authors |
Hasui K, Wang J, Tanaka Y, Izumo S, Eizuru Y, Matsuyama T |
Title |
Development of ultra-super sensitive immunohistochemistry and its application to the etiological study of adult T-cell leukemia/lymphoma. |
Journal |
|