KEGG   REACTION: R00036
Entry
R00036                      Reaction                               

Name
5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)
Definition
2 5-Aminolevulinate <=> Porphobilinogen + 2 H2O
Equation
2 C00430 <=> C00931 + 2 C00001
Reaction class
RC00918  C00430_C00931
RC01781  C00430_C00931
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Module
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868  Heme biosynthesis, animals and fungi, glycine => heme
M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Orthology
K01698  porphobilinogen synthase [EC:4.2.1.24]
Other DBs
RHEA: 24067

KEGG   RCLASS: RC00918
Entry
RC00918                     RClass                                 

Definition
C1b-C8x:*-*:C5a+N1a-C8y+N4x
C5a-C8y:O5a+*-*+C8y:C1b+C1b-C1b+C8x
N1a-N4x:*-C8y:C1b-C8x
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K01698  porphobilinogen synthase [EC:4.2.1.24]

KEGG   RCLASS: RC01781
Entry
RC01781                     RClass                                 

Definition
C1b-C8y:*-C8y:C1b+C5a-C1b+C8y
C5a-C8y:O5a+*-*+N4x:C1b+C1b-C1b+C8y
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K01698  porphobilinogen synthase [EC:4.2.1.24]

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