KEGG   REACTION: R00271
Entry
R00271                      Reaction                               

Name
acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Definition
Acetyl-CoA + H2O + 2-Oxoglutarate <=> (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA
Equation
Reaction class
RC00004  C00010_C00024
RC00067  C00026_C01251
RC02754  C00024_C01251
Enzyme
Pathway
rn00300  Lysine biosynthesis
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00433  Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Orthology
K01655  homocitrate synthase [EC:2.3.3.14]
K02594  homocitrate synthase NifV [EC:2.3.3.14]
K10977  methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
Other DBs
RHEA: 12932

KEGG   RCLASS: RC02754
Entry
RC02754                     RClass                                 

Definition
C1a-C1b:*-C1d:C5a-C6a
C5a-C6a:S2a+*-*+O6a:C1a+O5a-C1b+O6a
Reactant pair
Related class
Reaction
Enzyme
2.3.3.6         2.3.3.13        2.3.3.14        4.1.3.-
Pathway
rn00300  Lysine biosynthesis
rn00620  Pyruvate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
Orthology
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
K01655  homocitrate synthase [EC:2.3.3.14]
K02594  homocitrate synthase NifV [EC:2.3.3.14]
K10977  methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]

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