KEGG   REACTION: R00310
Entry
R00310                      Reaction                               

Name
protoheme ferro-lyase (protoporphyrin-forming)
Definition
Protoporphyrin + Fe2+ <=> Heme + 2 H+
Equation
Reaction class
RC01012  C00032_C02191
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00868  Heme biosynthesis, animals and fungi, glycine => heme
Orthology
K01772  protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]
Other DBs
RHEA: 22587

KEGG   RCLASS: RC01012
Entry
RC01012                     RClass                                 

Definition
N4x-N4y:*-Z:C8y+C8y-C8y+C8y
N4x-N4y:*-Z:C8y+C8y-C8y+C8y
Reactant pair
Related class
Reaction
Enzyme
4.99.1.1        4.99.1.3        4.99.1.4        4.99.1.9        
4.99.1.10       4.99.1.11       6.6.1.1
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K01772  protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]
K02190  sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02304  precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
K03403  magnesium chelatase subunit H [EC:6.6.1.1]
K03404  magnesium chelatase subunit D [EC:6.6.1.1]
K03405  magnesium chelatase subunit I [EC:6.6.1.1]
K03794  sirohydrochlorin ferrochelatase [EC:4.99.1.4]
K03795  sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
K22011  sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11]
K22013  magnesium dechelatase [EC:4.99.1.10]

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