KEGG   REACTION: R00709Help
Entry
R00709                      Reaction                               

Name
isocitrate:NAD+ oxidoreductase (decarboxylating)
Definition
Isocitrate + NAD+ <=> 2-Oxoglutarate + CO2 + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00114  C00026_C00311
RC02801  C00011_C00311
Enzyme
1.1.1.41        1.1.1.286
Pathway
rn00020  Citrate cycle (TCA cycle)
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01130  Biosynthesis of antibiotics
rn01200  Carbon metabolism
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Orthology
K00030  isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]
Other DBs
RHEA: 23635

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