KEGG   REACTION: R01224
Entry
R01224                      Reaction                               

Name
5-methyltetrahydrofolate:NADP+ oxidoreductase
Definition
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00081  C00143_C00440
Enzyme
Pathway
rn00670  One carbon pool by folate
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K00297  methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]
K24042  methionine synthase / methylenetetrahydrofolate reductase(NADPH) [EC:2.1.1.13 1.5.1.20]
Other DBs
RHEA: 19820

KEGG   REACTION: R07168
Entry
R07168                      Reaction                               

Name
5-methyltetrahydrofolate:NAD+ oxidoreductase
Definition
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00081  C00143_C00440
Enzyme
Pathway
rn00670  One carbon pool by folate
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
Orthology
K00297  methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]
K24042  methionine synthase / methylenetetrahydrofolate reductase(NADPH) [EC:2.1.1.13 1.5.1.20]
Other DBs
RHEA: 19824

KEGG   RCLASS: RC00081
Entry
RC00081                     RClass                                 

Definition
C1a-C1x:*-N1y:N1y-N1y
N1b-N1y:*-C1x:C1b+C8y-C1x+C8y
Reactant pair
Related class
Reaction
Enzyme
1.5.1.20        1.5.7.1
Pathway
rn00670  One carbon pool by folate
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Orthology
K00297  methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]
K24042  methionine synthase / methylenetetrahydrofolate reductase(NADPH) [EC:2.1.1.13 1.5.1.20]

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