KEGG   REACTION: R02860
Entry
R02860                      Reaction                               

Name
nicotine:(acceptor) 6-oxidoreductase (hydroxylating)
Definition
(R,S)-Nicotine + Acceptor + H2O <=> (S)-6-Hydroxynicotine + Reduced acceptor
Equation
Reaction class
RC00589  C01056_C16150
Enzyme
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00810  Nicotine degradation, pyridine pathway, nicotine => 2,6-dihydroxypyridine/succinate semialdehyde
Orthology
K19818  nicotine dehydrogenase subunit A [EC:1.5.99.4]
K19819  nicotine dehydrogenase subunit B [EC:1.5.99.4]
K19820  nicotine dehydrogenase subunit C [EC:1.5.99.4]
Other DBs
RHEA: 14772

KEGG   RCLASS: RC00589
Entry
RC00589                     RClass                                 

Definition
C8x-C8y:*-O1a:C8x+N5x-C8x+N5x
Reactant pair
Related class
Reaction
Enzyme
1.5.99.4        1.5.99.-        1.17.1.5        1.17.2.1
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K18029  nicotinate dehydrogenase subunit A [EC:1.17.2.1]
K18030  nicotinate dehydrogenase subunit B [EC:1.17.2.1]
K19818  nicotine dehydrogenase subunit A [EC:1.5.99.4]
K19819  nicotine dehydrogenase subunit B [EC:1.5.99.4]
K19820  nicotine dehydrogenase subunit C [EC:1.5.99.4]
K20171  3-succinoylpyridine monooxygenase subunit A
K20172  3-succinoylpyridine monooxygenase subunit C
K20445  nicotinate dehydrogenase FAD-subunit [EC:1.17.1.5]
K20446  nicotinate dehydrogenase small FeS subunit [EC:1.17.1.5]
K20447  nicotinate dehydrogenase large molybdopterin subunit [EC:1.17.1.5]
K20448  nicotinate dehydrogenase medium molybdopterin subunit [EC:1.17.1.5]

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