KEGG   REACTION: R02864
Entry
R02864                      Reaction                               

Name
S-Adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
Definition
Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin
Equation
Comment
multifunctional enzyme: siroheme synthase: sirohydrochlorin ferrochelatase (R03194+R03947+R02864)
following after R03947
Reaction class
RC01012  C00748_C05778
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Orthology
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02304  precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
K03794  sirohydrochlorin ferrochelatase [EC:4.99.1.4]
Other DBs
RHEA: 24363

KEGG   RCLASS: RC01012
Entry
RC01012                     RClass                                 

Definition
N4x-N4y:*-Z:C8y+C8y-C8y+C8y
N4x-N4y:*-Z:C8y+C8y-C8y+C8y
Reactant pair
Related class
Reaction
Enzyme
4.99.1.1        4.99.1.3        4.99.1.4        4.99.1.9        
4.99.1.10       4.99.1.11       6.6.1.1
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K01772  protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]
K02190  sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02304  precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
K03403  magnesium chelatase subunit H [EC:6.6.1.1]
K03404  magnesium chelatase subunit D [EC:6.6.1.1]
K03405  magnesium chelatase subunit I [EC:6.6.1.1]
K03794  sirohydrochlorin ferrochelatase [EC:4.99.1.4]
K03795  sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
K22011  sirohydrochlorin cobalto/nickelchelatase [EC:4.99.1.3 4.99.1.11]
K22013  magnesium dechelatase [EC:4.99.1.10]

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