KEGG   REACTION: R03165
Entry
R03165                      Reaction                               

Name
Hydroxymethylbilane hydro-lyase(cyclizing)
Definition
Hydroxymethylbilane <=> Uroporphyrinogen III + H2O
Equation
Reaction class
RC01861  C01024_C01051
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Module
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868  Heme biosynthesis, animals and fungi, glycine => heme
M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Orthology
K01719  uroporphyrinogen-III synthase [EC:4.2.1.75]
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
K13543  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Other DBs
RHEA: 18968

KEGG   RCLASS: RC01861
Entry
RC01861                     RClass                                 

Definition
C1b-C1x:C8y+*-*+C8y:C8y-C8y
C1b-C1x:O1a+*-*+C8y:C8y-C8y
C8x-C8y:*-C1x:C8y+N4x-C8y+N4x
C8y-C8y:C1b+*-*+C1x:C8y+N4x-C8y+N4x
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K01719  uroporphyrinogen-III synthase [EC:4.2.1.75]
K13542  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
K13543  uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]

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