KEGG   REACTION: R03947
Entry
R03947                      Reaction                               

Name
S-Adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
Definition
Precorrin 2 + NAD+ <=> Sirohydrochlorin + NADH + H+
Equation
Comment
multifunctional enzyme: siroheme synthase: precorrin-2 dehydrogenase (R03194+R03947+R02864)
following after R03194, subsequently R02864
Reaction class
RC00001  C00003_C00004
RC01034  C02463_C05778
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Module
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Orthology
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02304  precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]
Other DBs
RHEA: 15616

KEGG   RCLASS: RC01034
Entry
RC01034                     RClass                                 

Definition
C1x-C8x:*-*:C8y+C8y-C8y+C8y
N1x-N5x:*-*:C2y+C2y-C8y+C8y
N2x-N4x:*-*:C2y+C2y-C8y+C8y
N4x-N5x:*-*:C8y+C8y-C8y+C8y
Reactant pair
Related class
Reaction
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
K02304  precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:1.3.1.76 4.99.1.4]

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