KEGG   REACTION: R04418
Entry
R04418                      Reaction                               

Name
5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase
Definition
2-Hydroxy-5-carboxymethylmuconate semialdehyde + NAD+ + H2O <=> 5-Carboxymethyl-2-hydroxymuconate + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00254  C04186_C04642
Enzyme
1.1.1.312       1.2.1.60
Pathway
rn00350  Tyrosine metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00533  Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
Orthology
K00151  5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase [EC:1.2.1.60]
K10219  2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312]
Other DBs
RHEA: 15684

KEGG   RCLASS: RC00254
Entry
RC00254                     RClass                                 

Definition
C4a-C6a:*-O6a:C2c+O4a-C2c+O6a
Reactant pair
Related class
Reaction
Enzyme
1.1.1.312       1.2.1.60        1.2.1.82        1.2.1.85        
1.2.1.-         1.2.99.10       1.14.14.95      1.14.14.114     
1.14.99.44
Pathway
rn00350  Tyrosine metabolism
rn00622  Xylene degradation
rn00903  Limonene and pinene degradation
rn00906  Carotenoid biosynthesis
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
RModule
RM009  Meta-cleavage of dihydroxylated aromatic ring
RM012  Dihydroxylation and meta-cleavage of aromatic ring, type 3a
Orthology
K00151  5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase [EC:1.2.1.60]
K10210  diapolycopene oxygenase [EC:1.14.99.44]
K10217  aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.32 1.2.1.85]
K10219  2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312]
K17819  beta-apo-4'-carotenal oxygenase [EC:1.2.1.82]

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