KEGG   REACTION: R05224
Entry
R05224                      Reaction                               

Definition
Hydrogenobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Hydrogenobyrinate a,c diamide + 2 Orthophosphate + 2 L-Glutamate + 2 ADP
Equation
C06399 + 2 C00064 + 2 C00002 + 2 C00001 <=> C06503 + 2 C00009 + 2 C00025 + 2 C00008
Comment
multi-step reaction
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064
RC01301  C06399_C06503
Enzyme
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00925  Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
Orthology
K02224  cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
Other DBs
RHEA: 12547

KEGG   RCLASS: RC01301
Entry
RC01301                     RClass                                 

Definition
C5a-C6a:N1a+*-*+O6a:C1b+O5a-C1b+O6a
C5a-C6a:N1a+*-*+O6a:C1b+O5a-C1b+O6a
Reactant pair
Related class
Reaction
Enzyme
6.3.5.9         6.3.5.11        6.3.5.12
Pathway
rn00860  Porphyrin and chlorophyll metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Orthology
K02224  cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
K22012  Ni-sirohydrochlorin a,c-diamide synthase [EC:6.3.5.12]

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